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- 2025年07月16日
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- 技术资料
- 保存条件：
-20℃
- 保质期：
6个月
- 英文名：
Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)
- 库存：
10000
- 供应商：
钰博生物
血小板反应蛋白解整合素金属肽酶8(ADAMTS8)重组蛋白
适用生物 Homo sapiens (Human，人)
血小板反应蛋白解整合素金属肽酶8(ADAMTS8)重组蛋白
产品应用 SDS-PAGE; WB; ELISA; IP. 规格 50ug
分子量 7.7kDa 价格 请咨询当地代理商
纯度 > 95%
来源 原核表达
yb-8292R DPY19L4DPY19L4蛋白抗体 浓度1mg/ml
yb-8294R DPP9二肽基肽酶9抗体 浓度1mg/ml
yb-8295R DPP8二肽基肽酶8抗体 浓度1mg/ml
yb-12037R DRD4多巴胺受体D4抗体 浓度1mg/ml
yb-8293R DQX1DQX1蛋白抗体 浓度1mg/ml
yb-7117R DDX5三磷酸腺苷依赖解旋酶ddx5抗体 浓度1mg/ml
yb-8005R phospho-DDX5 (Tyr593)磷酸化三磷酸腺苷依赖解旋酶ddx5抗体 浓度1mg/ml
yb-11862R DYX2/KIAA0319阅读障碍相关蛋白DLX2抗体 浓度1mg/ml
yb-10046R Dystrobrevin alpha肌营养蛋白α抗体 浓度1mg/ml
yb-10064R CD299CD299抗体 浓度1mg/ml
yb-11546R DUSP6双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体 浓度1mg/ml
yb-11547R Dab1磷脂蛋白受体Dab1抗体 浓度1mg/ml
yb-11548R Phospho-Dab1 (Tyr198) 磷酸化磷脂蛋白受体Dab1抗体 浓度1mg/ml
yb-11550R DLX2同源转录因子DLX2抗体 浓度1mg/ml
yb-2983R Desmocollin 2桥粒糖蛋白2/桥粒糖蛋白3抗体 浓度1mg/ml
yb-6307R Desmocollin 1桥粒糖蛋白1抗体 浓度1mg/ml
yb-6630R Destrin 19肌动蛋白解聚因子19抗体 浓度1mg/ml
yb-6929R DCTN1动力蛋白激活蛋白1抗体 浓度1mg/ml
yb-6725R Desmoglein 1桥粒芯糖蛋白1 浓度1mg/ml
yb-5801R DLC1胞浆动力蛋白轻链1抗体 浓度1mg/ml
yb-11827R DRGX背根神经节同源蛋白DRGX抗体 浓度1mg/ml
yb-5909R DeltaDDeltaD抗体 浓度1mg/ml
yb-5938R DAT1神经细胞特异性转录因子DAT1抗体 浓度1mg/ml
yb-6234R DOK3对接蛋白3抗体 浓度1mg/ml
yb-5931R DCUN1D2DCN1样蛋白2抗体 浓度1mg/ml
yb-4949R DNAJB6热休克蛋白J2抗体 浓度1mg/ml
yb-6259R Dyrk1B双特异性酪氨酸磷酸化调节激酶1B抗体 浓度1mg/ml
适用生物 Homo sapiens (Human，人)
血小板反应蛋白解整合素金属肽酶8(ADAMTS8)重组蛋白
产品应用 SDS-PAGE; WB; ELISA; IP. 规格 50ug
分子量 7.7kDa 价格 请咨询当地代理商
纯度 > 95%
来源 原核表达
Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)
FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
| Organism species | Homo sapiens (Human) |
| Product No. | RPK208Hu01 |
| Source | Prokaryotic expression |
| Host | E.coli |
| Purity | > 95% |
| UOM | 50ug |
| Predicted Molecular Mass | 7.7kDa |
| Predicted isoelectric point | 6.3 |
| Applications | SDS-PAGE; WB; ELISA; IP. |
| Endotoxin Level | <1.0EU per 1µg (determined by the LAL method) |
| Subcellular Location | Secreted, extracellular space, extracellular matrix |
| Residues | Leu832~Leu889 (Accession # Q9UP79) with N-terminal His-Tag |
| Formulation | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
SEQUENCES
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSGSEF -LHAQWVLGD WSECSSTCGA GWQRRTVECR DPSGQASATC NKALKPEDAK PCESQLCPL
MGHHHHHHSGSEF -LHAQWVLGD WSECSSTCGA GWQRRTVECR DPSGQASATC NKALKPEDAK PCESQLCPL
USAGE
Reconstitute in sterile PBS, pH7.2-pH7.4.
STORAGE AND STABILITY
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8oC for one month. Aliquot and store at -80oC for 12 months.
血小板反应蛋白解整合素金属肽酶8(ADAMTS8)重组蛋白Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
血小板反应蛋白解整合素金属肽酶8(ADAMTS8)重组蛋白Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
About the MARKER (complimentary)
血小板反应蛋白解整合素金属肽酶8(ADAMTS8)重组蛋白Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
yb-8289R DPY19L1短粗矮胖19蛋白样1抗体 浓度1mg/ml
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
yb-8292R DPY19L4DPY19L4蛋白抗体 浓度1mg/ml
yb-8294R DPP9二肽基肽酶9抗体 浓度1mg/ml
yb-8295R DPP8二肽基肽酶8抗体 浓度1mg/ml
yb-12037R DRD4多巴胺受体D4抗体 浓度1mg/ml
yb-8293R DQX1DQX1蛋白抗体 浓度1mg/ml
yb-7117R DDX5三磷酸腺苷依赖解旋酶ddx5抗体 浓度1mg/ml
yb-8005R phospho-DDX5 (Tyr593)磷酸化三磷酸腺苷依赖解旋酶ddx5抗体 浓度1mg/ml
yb-11862R DYX2/KIAA0319阅读障碍相关蛋白DLX2抗体 浓度1mg/ml
yb-10046R Dystrobrevin alpha肌营养蛋白α抗体 浓度1mg/ml
yb-10064R CD299CD299抗体 浓度1mg/ml
yb-11546R DUSP6双特异性蛋白磷酸酶6/丝裂原活化蛋白激酶磷酸酶3抗体 浓度1mg/ml
yb-11547R Dab1磷脂蛋白受体Dab1抗体 浓度1mg/ml
yb-11548R Phospho-Dab1 (Tyr198) 磷酸化磷脂蛋白受体Dab1抗体 浓度1mg/ml
yb-11550R DLX2同源转录因子DLX2抗体 浓度1mg/ml
yb-2983R Desmocollin 2桥粒糖蛋白2/桥粒糖蛋白3抗体 浓度1mg/ml
yb-6307R Desmocollin 1桥粒糖蛋白1抗体 浓度1mg/ml
yb-6630R Destrin 19肌动蛋白解聚因子19抗体 浓度1mg/ml
yb-6929R DCTN1动力蛋白激活蛋白1抗体 浓度1mg/ml
yb-6725R Desmoglein 1桥粒芯糖蛋白1 浓度1mg/ml
yb-5801R DLC1胞浆动力蛋白轻链1抗体 浓度1mg/ml
yb-11827R DRGX背根神经节同源蛋白DRGX抗体 浓度1mg/ml
yb-5909R DeltaDDeltaD抗体 浓度1mg/ml
yb-5938R DAT1神经细胞特异性转录因子DAT1抗体 浓度1mg/ml
yb-6234R DOK3对接蛋白3抗体 浓度1mg/ml
yb-5931R DCUN1D2DCN1样蛋白2抗体 浓度1mg/ml
yb-4949R DNAJB6热休克蛋白J2抗体 浓度1mg/ml
yb-6259R Dyrk1B双特异性酪氨酸磷酸化调节激酶1B抗体 浓度1mg/ml
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文献和实验相关实验
用；JAK抑制剂虽有效但存在安全风险；P2Y14R抑制剂则通过cAMP/PKA/CREB通路缓解肠上皮损伤。中药如黄芩-黄连药对和青hao素通过多靶点调控炎症与免疫。此外，表观遗传靶点（如Sirpa增强子RNA）、蛋白互作靶点（PDIA1、NOC4L）及纳米递送系统调控巨噬细胞极化等新技术，为UC治疗开辟新路径。 临床诊断 溃疡性结肠炎（UC）的诊断需综合胃肠道症状、实验室检查、结肠镜表现及病理结果。血液检查在轻症时可能正常，但中重度活动期常出现贫血、白细胞和血小板增多及C反应蛋白升高。粪便钙卫蛋白
。胞浆内蛋白在蛋白酶作用下降解成肽段，依次被热休克蛋白HSP70和HSP90传递给膜上的TAP (tansporter associated with antigen processing) ，同时，在蛋白酶的作用下进一步被剪切成小肽。 小肽由TAP经HSP96传递给内质网内新合成的MHC I类分子上，最后由MHC I类分子将结合的抗原小肽托出细胞膜外。细胞外物质经专职APC吞噬（phagocytosis，指颗粒抗原）、胞饮（pinocytosis, 指可溶性抗原）或内吞（endocytosis
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血小板反应蛋白解整合素金属肽酶8(ADAMTS8)重组蛋白
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