- ¥80
- 上海钰博
- 进口/国产
- YB801Hu01
- 2026年09月22日
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- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
6个月
- 英文名：
Recombinant Alkaline Sphingomyelinase (Alk-Smase)
- 库存：
10000
- 供应商：
钰博生物
碱性鞘磷脂磷酸二酯酶(Alk-Smase)重组蛋白
适用生物 Homo sapiens (Human，人)
碱性鞘磷脂磷酸二酯酶(Alk-Smase)重组蛋白
产品应用 SDS-PAGE; WB; ELISA; IP. 规格 50ug
分子量 26.5kDa 价格 请咨询当地代理商
纯度 > 95%
来源 原核表达
yb-1286R CD40LCD40L抗体 浓度1mg/ml
yb-10033R Alpha s1 Caseinα-s1酪蛋白抗体 浓度1mg/ml
yb-0716R CIDEBCIDEB抗体 浓度1mg/ml
yb-1186R Scavenging Receptor SR-BI高密度脂蛋白受体/清道夫受体抗体 浓度1mg/ml
yb-9124R COPS7A信号转导蛋白亚基7A抗体 浓度1mg/ml
yb-0615R Survivin细胞凋亡抑制因子抗体 浓度1mg/ml
yb-0936R Clostridium perfringens type DD型产气荚膜梭菌抗体 浓度1mg/ml
yb-0063R Calcitonin降钙素抗体 浓度1mg/ml
yb-15094R C20orf1420号染色体开放阅读框14抗体 浓度1mg/ml
yb-0743R CTGF结缔组织生长因子抗体 浓度1mg/ml
yb-1179R CTLA4细胞毒性T细胞抗原-4抗体 浓度1mg/ml
yb-0124R Calcitonin receptor降钙素受体抗体 浓度1mg/ml
yb-15065R C1orf381号染色体开放阅读框38抗体 浓度1mg/ml
yb-0727R CXorf36脱羧酶蛋白体36抗体 浓度1mg/ml
yb-1050R Connexin-40间隙连接蛋白40抗体 浓度1mg/ml
yb-0651R Connexin 43间隙连接蛋白43抗体 浓度1mg/ml
yb-0652R Connexin-45间隙连接蛋白45抗体 浓度1mg/ml
yb-1009R CXCR1细胞表面趋化因子受体1抗体 浓度1mg/ml
yb-0461R CYP450细胞色素P450单氧化酶抗体 浓度1mg/ml
yb-0013R Cytochrome C细胞色素C抗体 浓度1mg/ml
yb-1244R CK1细胞角蛋白1抗体 浓度1mg/ml
yb-0271R Cytomegalovirus pp65 巨细胞病毒PP65/CMV低基质磷脂蛋白抗体 浓度1mg/ml
适用生物 Homo sapiens (Human，人)
碱性鞘磷脂磷酸二酯酶(Alk-Smase)重组蛋白
产品应用 SDS-PAGE; WB; ELISA; IP. 规格 50ug
分子量 26.5kDa 价格 请咨询当地代理商
纯度 > 95%
来源 原核表达
Recombinant Alkaline Sphingomyelinase (Alk-Smase)
FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
| Organism species | Homo sapiens (Human) |
| Product No. | RPA801Hu01 |
| Source | Prokaryotic expression |
| Host | E.coli |
| Purity | > 95% |
| UOM | 50ug |
| Predicted Molecular Mass | 26.5kDa |
| Applications | SDS-PAGE; WB; ELISA; IP. |
| Endotoxin Level | <1.0EU per 1µg (determined by the LAL method) |
| Residues | His234~Ala458 (Accession # Q6UWV6) with N-terminal His-Tag |
| Formulation | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
SEQUENCES
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSGS-HLTDRLN LIITSDHGMT TVDKRAGDLV EFHKFPNFTF RDIEFELLDY GPNGMLLPKE GRLEKVYDAL KDAHPKLHVY KKEAFPEAFH YANNPRVTPL LMYSDLGYVI HGRINVQFNN GEHGFDNKDM DMKTIFRAVG PSFRAGLEVE PFESVHVYEL MCRLLGIVPE ANDGHLATLL PMLHTESALP PDGRPTLLPK GRSALPPSSR PLLVMGLLGT VILLSEVA
MGHHHHHHSGS-HLTDRLN LIITSDHGMT TVDKRAGDLV EFHKFPNFTF RDIEFELLDY GPNGMLLPKE GRLEKVYDAL KDAHPKLHVY KKEAFPEAFH YANNPRVTPL LMYSDLGYVI HGRINVQFNN GEHGFDNKDM DMKTIFRAVG PSFRAGLEVE PFESVHVYEL MCRLLGIVPE ANDGHLATLL PMLHTESALP PDGRPTLLPK GRSALPPSSR PLLVMGLLGT VILLSEVA
USAGE
Reconstitute in sterile PBS, pH7.2-pH7.4.
STORAGE AND STABILITY
碱性鞘磷脂磷酸二酯酶(Alk-Smase)重组蛋白Storage: Avoid repeated freeze/thaw cycles. Store at 2-8oC for one month. Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
About the MARKER (complimentary)
碱性鞘磷脂磷酸二酯酶(Alk-Smase)重组蛋白Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
yb-1330R CKIP-1酪蛋白激酶2相互作用蛋白1抗体 浓度1mg/ml
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
yb-1286R CD40LCD40L抗体 浓度1mg/ml
yb-10033R Alpha s1 Caseinα-s1酪蛋白抗体 浓度1mg/ml
yb-0716R CIDEBCIDEB抗体 浓度1mg/ml
yb-1186R Scavenging Receptor SR-BI高密度脂蛋白受体/清道夫受体抗体 浓度1mg/ml
yb-9124R COPS7A信号转导蛋白亚基7A抗体 浓度1mg/ml
yb-0615R Survivin细胞凋亡抑制因子抗体 浓度1mg/ml
yb-0936R Clostridium perfringens type DD型产气荚膜梭菌抗体 浓度1mg/ml
yb-0063R Calcitonin降钙素抗体 浓度1mg/ml
yb-15094R C20orf1420号染色体开放阅读框14抗体 浓度1mg/ml
yb-0743R CTGF结缔组织生长因子抗体 浓度1mg/ml
yb-1179R CTLA4细胞毒性T细胞抗原-4抗体 浓度1mg/ml
yb-0124R Calcitonin receptor降钙素受体抗体 浓度1mg/ml
yb-15065R C1orf381号染色体开放阅读框38抗体 浓度1mg/ml
yb-0727R CXorf36脱羧酶蛋白体36抗体 浓度1mg/ml
yb-1050R Connexin-40间隙连接蛋白40抗体 浓度1mg/ml
yb-0651R Connexin 43间隙连接蛋白43抗体 浓度1mg/ml
yb-0652R Connexin-45间隙连接蛋白45抗体 浓度1mg/ml
yb-1009R CXCR1细胞表面趋化因子受体1抗体 浓度1mg/ml
yb-0461R CYP450细胞色素P450单氧化酶抗体 浓度1mg/ml
yb-0013R Cytochrome C细胞色素C抗体 浓度1mg/ml
yb-1244R CK1细胞角蛋白1抗体 浓度1mg/ml
yb-0271R Cytomegalovirus pp65 巨细胞病毒PP65/CMV低基质磷脂蛋白抗体 浓度1mg/ml
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文献和实验相关实验
的靶点分布呈现出明显集中的特点，主要集中在少数几个关键的激酶家族上[19]。 表3. 获批激酶抑制剂的靶点分布[19]。 总的来说，已获批激酶抑制剂的靶点分布高度集中于驱动癌症和自身免疫性疾病的关键信号通路上，尤其是酪氨酸激酶家族。 MCE 相关产品 一、主要激酶家族的重组蛋白:含常见突变体如 EGFR L858R/T790M/C797S（www
【热门靶点解析】TGF-β信号通路+重要作用+药物研发！（建议收藏）
反应，分为TGF-β1/2/3和BMP两条分支，分别激活Smad2/3和Smad1/5/8。TGF-β配体首先结合Ⅱ型受体（TβRⅡ），招募Ⅰ型受体（TβRⅠ/ALK5）形成复合物，TβRⅡ磷酸化激活TβRⅠ，后者进一步磷酸化Smad2/3。活化的R-Smad与Smad4结合，转入细胞核，与转录因子共同调控靶基因表达，介导细胞分化、凋亡、上皮-间质转化及免疫调节等生物学功能。该过程受Ⅲ型受体（TβRⅢ）辅助调控，确保信号精确传递。 TGF-β1的重要作用 1.TGF-β1定向诱导T细胞的分化 TGF
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碱性鞘磷脂磷酸二酯酶(Alk-Smase)重组蛋白
¥80
