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- 文献和实验
- 技术资料
- 英文名：
4-Hydroxy Tamoxifen
- 供应商：
上海汇谱仪器有限公司
- CAS号：
58047-06-3
- 规格：
1-100mg
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文献和实验Tamoxifen administration to mice
One of the uses of tamoxifen in the lab is the activation of enzymes deactivated via an estrogen-binding domain, like Cre-ERT (Cre-LBD). Tamoxifen is an estrogen analogue that binds with higher affinity than estrogen to altered estrogen
Therapeutic Drug Monitoring of Tamoxifen Using LC-MS/MS
) and 4-hydroxy-N-desmethyltamoxifen (endoxifen), may be clinically useful for guiding treatment decisions. Two significant barriers to tamoxifen efficacy are: (1) variability in conversion of tamoxifen into the potent antiestrogenic metabolite, endoxifen
Generating Tamoxifen-Inducible Cre Alleles to Investigate Myogenesis in Mice
using Cre recombinase expressed via a tissue specific promoter/enhancer allows phenotypic analyses of selected tissues, but lacks temporal control. Recent development of the tamoxifen-inducible Cre-ERT2 offers both cell type-specific and temporal control
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