Zona Pellucida Glycoprotein 3

yb183236 产品详细信息
Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) 抗体
anti-Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) antibody
抗原
Zona Pellucida Glycoprotein 3 (ZP3)
别名 zp3.2, Zp-3, ZP3A, ZP3B, ZPC, Zp-3B
抗原表位
其他选择 C-Term
适用
其他选择 兔, 牛, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品细节Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human ZP3
序列 NKGDCGTPSH SRRQPHVMSQ WSRSASRNRR HVTEEADVTV GATDLPGQEW
预测反应 Bovine : 100 %, Human : 100 %, Rabbit : 100 %
产品特性 This is a rabbit polyclonal antibody against ZP3. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
目标详细情况Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) 抗体
别名 ZP3
背景 The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus, however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene
分子量 47 kDa
基因ID 7784
研究领域 Reproduction
使用细节 Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 424 AA
限制 仅限研究用
贮存及处理 Zona Pellucida Glycoprotein 3 (ZP3) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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