AMPK Alpha2 (PRKAA2) (C-Term),

AMPK Alpha2 (PRKAA2) (C-Term), (AA 453-483) 抗体抗原
AMPK Alpha2 (PRKAA2)
抗原表位
C-Term, AA 453-483
适用
人
宿主
兔
克隆类型 (克隆位点)
多克隆 (RB11657)
应用范围
Western Blotting (WB), 免疫组织化学（IHC）
Pubmed 2个引用可参考
规格 400 μL
发货至 中国 (更改)
发货时间 9至13个工作日
产品编号 yb391608
产品细节 AMPK Alpha2 (PRKAA2) (C-Term), (AA 453-483) 抗体
免疫原 This AMPK alpha2 (PRKAA2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-483 AA from the C-terminal region of human AMPK alpha2 (PRKAA2).
克隆位点 RB11657
亚型 Ig
特异性 This PRKAA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 461~490 amino acids from the C-terminal region of human PRKAA2.
预测反应 Mouse (Murine),Rat (Rattus)
纯化方法 This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
目标详细情况 AMPK Alpha2 (PRKAA2) (C-Term), (AA 453-483) 抗体
背景 The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Synonyms: EC 2.7.11.1, AMPK alpha-2 chain
分子量 62189 DA
基因ID 5563
UniProt P54646
研究领域 Phospho-specific antibodies, Protein Modifications, Metabolism, Cell Structure
使用细节 AMPK Alpha2 (PRKAA2) (C-Term), (AA 453-483) 抗体
应用备注 WB = 1:1000, IHC = 1:10-50
限制 仅限研究用
贮存及处理 AMPK Alpha2 (PRKAA2) (C-Term), (AA 453-483) 抗体
状态 Liquid
浓度 2 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months