CD44 (CD44) 抗体

CD44 (CD44) 抗体抗原
CD44 (CD44)
别名 AU023126, AW121933, AW146109, HERMES, Ly-24, Pgp-1, CD44A, METAA, RHAMM, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (VFF-11)
标记
其他选择 This CD44 antibody is un-conjugated
应用范围
其他选择 Immunohistochemistry (Frozen Sections) (IHC (fro)), 流式细胞分析技术（FACS）, Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), 免疫组织化学石蜡技术（IHC-P）
Pubmed 2个引用可参考
规格 0.1 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb118667
CD44抗体: 产品细节 CD44 (CD44) 抗体
免疫原 Recombinant protein corresponding to exon variant 4 of the CD44 molecule.
克隆位点 VFF-11
亚型 IgG1
特异性 This antibody specifically recognises an epitope encoded by exon v4 on the variant portion of human CD44.
纯化方法 Protein A affinity purified immunoglobulin fraction
CD44:目标详细情况 CD44 (CD44) 抗体
别名 CD44
背景 CD44 variant4 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. The CD44 Molecule belongs to a family of cellular adhesion molecule found on a wide range of normal and malignant cells in epithelial, mesothelial and haematopoietic tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been shown to be associated with metastasis and poor prognosis in certain human malignancies, such as breast cancer.Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I
基因ID 960
NCBI登录号 NP_000601
UniProt P16070
研究领域 Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Cancer, Cell Cycle
使用细节 CD44 (CD44) 抗体
应用备注 Flow cytometry: 1:50, use 10 μL of the suggested working dilution to label 10^6 cells. Immunohistochemistry: 1:50-1:500 for frozen and paraffin sections. Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 CD44 (CD44) 抗体
浓度 0.5 mg/mL
缓冲液 PBS with 0.01 % Thimerosal as preservative.
储存液 Thimerosal (Merthiolate)
注意事项 This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.