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- 文献和实验
- 技术资料
- 供应商:
安元生物
- 规格:
10 µg
产品概述
mutant p53 (human)安元生物是高纯度酶制剂产品,经过严格的质量控制和活性检测,适用于分子生物学实验、基因工程和体外反应体系。
产品参数
| 产品名称 | 试剂(mutant p53 (human)) |
| 品牌 | Pierce |
| 货号 | RP821 |
| 保存条件 | -20℃保存 |
| 有效期 | 12个月 |
产品特点
1. 高催化活性:经过严格的酶活性检测。
2. 高纯度:SDS-PAGE验证,无杂蛋白污染。
3. 批次稳定:多批次间活性一致。
应用领域
基因编辑、分子克隆、DNA/RNA操作、基因组学研究等。
注意事项
1. 仅供科研使用,不可用于临床诊断或治疗。
2. 请于-20℃保存,避免反复冻融。
关键词
mutant p53 (human)、酶制剂、分子生物学试剂


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文献和实验Generation and Characterization of p53 Mutant Mice
p53 is one of the most well-characterized members of the tumor suppressor gene family. The role of p53 in controlling cellular homeostasis has proven critical, with over half of all human tumors having either lost or mutated p53
Lung-Specific Expression of Mutant p53 as Mouse Model for Lung Cancer
where adenocarcinomas often arise. In human lung cancer, both the frequency and type of mutations in the p53 gene can act as fingerprints providing information about external etiological agents, carcinogen exposure, and host factors affecting the carcinogenesis process (6) .
Detection of K-ras and p53 Mutations by Mutant-Enriched PCR-RFLP
, since they fulfill many criteria that link their de novo appearance to the process of field cancerization (4 ). Oncogene mutations of the ras - and p53 -type are found in chronic smokers and patients with preneoplastic and neoplastic lesions
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