Thioredoxin (TXN) (N-Term) 抗体

Thioredoxin (TXN) (N-Term) 抗体抗原
Thioredoxin (TXN)
别名
trx, TXN, ARABIDOPSIS THALIANA THIOREDOXIN H-TYPE 1, ATTRX H1, ATTRX1, THIOREDOXIN, thioredoxin H-type 1, ATH5, ATTRX5, F27F5.21, F27F5_21, LIV1, LOCUS OF INSENSITIVITY TO VICTORIN 1, THIOREDOXIN H-TY ... show more
抗原表位
其他选择 N-Term
适用
其他选择 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 酵素免疫分析法（EIA）, Western Blotting (WB)
Pubmed 4个引用可参考
规格 0.4 mL
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb356853
产品细节 Thioredoxin (TXN) (N-Term) 抗体
免疫原 KLH conjugated synthetic peptide selected from the N-terminal region of Human TrX.
亚型 Ig
特异性 This antibody is specific to Thioredoxin (TRX) (N-term).
交叉反应 （详细） Species reactivity (tested):Human.
纯化方法 Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
目标详细情况 Thioredoxin (TXN) (N-Term) 抗体
别名 Thioredoxin / TRX1
背景 Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1.Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.Synonyms: ADF, ATL-derived factor, SASP, Surface-associated sulphydryl protein, TRDX, TRX, TXN
分子量 11737 Da
基因ID 7295, 9606
UniProt P10599
研究领域 Coagulation, Enzymes, Metabolism
使用细节 Thioredoxin (TXN) (N-Term) 抗体
应用备注 ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Thioredoxin (TXN) (N-Term) 抗体
状态 Liquid
浓度 0.25 mg/mL
缓冲液 PBS containing 0.09 % (W/V) Sodium Azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.