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- 详细信息
- 技术资料
- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
Cyclin D3 (CCND3) (C-Term) 抗体
- 规格：
0.1ml/0.2ml
Cyclin D3 (CCND3) (C-Term) 抗体抗原
Cyclin D3 (CCND3)
别名 zgc:103502, CCND3, 9230106B05Rik, AA682053, AL024085, AW146355, C78795
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 犬, 牛, 猪, 人, 小鸡
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 免疫组织化学（IHC）, Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb184169
产品细节 Cyclin D3 (CCND3) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human CCND3
序列 CQEQIEAALR ESLREASQTS SSPAPKAPRG SSSQGPSQTS TPTDVTAIHL
预测反应 Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Sheep : 100 %, Guinea pig : 90 %, Chicken : 80 %
产品特性 This is a rabbit polyclonal antibody against CCND3. It was validated on Western Blot and immunohistochemistry.
纯化方法 Affinity Purified
目标详细情况 Cyclin D3 (CCND3) (C-Term) 抗体
别名 CCND3
背景 CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
分子量 33 kDa
基因ID 896
NCBI登录号 NP_001751, NM_001760
UniProt P30281
使用细节 Cyclin D3 (CCND3) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 292 AA
限制 仅限研究用
贮存及处理Cyclin D3 (CCND3) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
Cyclin D3 (CCND3)
别名 zgc:103502, CCND3, 9230106B05Rik, AA682053, AL024085, AW146355, C78795
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 犬, 牛, 猪, 人, 小鸡
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 免疫组织化学（IHC）, Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb184169
产品细节 Cyclin D3 (CCND3) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human CCND3
序列 CQEQIEAALR ESLREASQTS SSPAPKAPRG SSSQGPSQTS TPTDVTAIHL
预测反应 Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Sheep : 100 %, Guinea pig : 90 %, Chicken : 80 %
产品特性 This is a rabbit polyclonal antibody against CCND3. It was validated on Western Blot and immunohistochemistry.
纯化方法 Affinity Purified
目标详细情况 Cyclin D3 (CCND3) (C-Term) 抗体
别名 CCND3
背景 CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
分子量 33 kDa
基因ID 896
NCBI登录号 NP_001751, NM_001760
UniProt P30281
使用细节 Cyclin D3 (CCND3) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 292 AA
限制 仅限研究用
贮存及处理Cyclin D3 (CCND3) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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Cyclin D3 (CCND3) (C-Term) 抗体
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