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- 2025年07月16日
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- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
Fas Ligand (TNF Superfamily, Member 6) (FASL) 抗体
- 规格：
0.1ml/0.2ml
Fas Ligand (TNF Superfamily, Member 6) (FASL)
别名 fasl, FASL, FASLG, FAS, TNFRSF6, zgc:162027, TNFSF6, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, Fas-L, Faslg, Tnfsf6, gld, Apt1Lg1, Fasl
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (1OF2)
标记
其他选择 非结合性
应用范围
其他选择 酵素免疫分析法（EIA）, 流式细胞分析技术（FACS）, 免疫沉淀（IP）
Pubmed 2个引用可参考
规格 0.1 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb120318
产品细节 Fas Ligand (TNF Superfamily, Member 6) (FASL) 抗体
免疫原 Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line.
克隆位点 1OF2
亚型 IgG1
特异性 This antibody recognises the CD178 cell surface antigen. This antibody may be used in combination with clone 14C2 (MCA2409) in ELISA assays. Clone 10F2 is reported to block the activity of Fas ligand. We recommend the use of SM2268LE for such studies.
纯化方法 Affinity Chromatography on Protein G
目标详细情况 Fas Ligand (TNF Superfamily, Member 6) (FASL) 抗体
别名 CD178 / Fas Ligand
背景 CD178 is a 40 kDa glycoprotein also known as Fas ligand (CD95L). CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
基因ID 356
NCBI登录号 NP_000630
UniProt P48023
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节Fas Ligand (TNF Superfamily, Member 6) (FASL) 抗体
应用备注 Flow Cytometry: 1/25 - 1/50, Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. ELISA. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Fas Ligand (TNF Superfamily, Member 6) (FASL) 抗体
浓度 1.0 mg/mL
缓冲液 PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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文献和实验人Fas 配体(FasL) 酶联免疫分析（ ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中Fas 配体(FasL) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中 人 Fas 配体 (FasL) 水平。用纯化的 人 Fas 配体 (FasL) 抗体 包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 Fas 配体 (FasL
引起细胞一系列特征性变化，使细胞死亡。 Receptors in the TNF receptor family are associated with the induction of apoptosis, as well as inflammatory signaling. The Fas receptor (CD95) mediates apoptotic signaling by Fas-ligand expressed on the surface
-gene and Fas ligand (FasL)-gene transfection through the use of electroporation, and suggest that the Fas-FasL system is a good target for the induction of apoptosis-mediated antitumor activity. The Fas receptor/ligand system induces apoptosis and plays
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