- 询价
- 沪震生物
- 进口/国产
- hz713Hu01
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
12个月
- 英文名：
Recombinant CCAAT/Enhancer Binding Protein Beta (CEBPb)
- 库存：
100
- 供应商：
上海沪震
FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
Organism species Homo sapiens (Human)
Product No. RPA713Hu01
Source Prokaryotic expression
Host E.coli
Purity > 95%
UOM 50ug
Predicted Molecular Mass n/a
Predicted isoelectric point n/a
Applications SDS-PAGE; WB; ELISA; IP.
Endotoxin Level <1.0EU per 1µg (determined by the LAL method)
Subcellular Location n/a
CCAAT增强子结合蛋白β(CEBPβ)重组蛋白Residues n/a
Formulation Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
USAGE
Reconstitute in sterile PBS, pH7.2-pH7.4.
STORAGE AND STABILITY
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8oC for one month. Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
About the MARKER (complimentary)
Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
CCAAT增强子结合蛋白β(CEBPβ)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
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文献和实验为什么女性更容易得阿尔茨海默症？Nature：叶克强团队最新研究揭开背后之谜
，叶克强团队揭示了 CCAAT 增强子结合蛋白 β（C/EBPβ）通过增加天冬酰胺内肽酶（AEP）的表达，会在阿尔兹海默症发病机制中起到关键作用，并进一步提出激活 C/EBPβ/AEP 神经信号通路能够介导阿尔兹海默症的病变，相关综述文章于 2020 年发表于 Experimental& Molecular Medicine、Translational Neurodegeneration。 既然卵泡刺激素是女性更易患阿尔兹海默症的重要因素，那它是如何影响这条信号通路，进而影响阿尔兹海默症的产生
一、转化生长因子-β（TGF-β） 转化生长因子-β（transforming growth factor-β,TGF-β)是属于一组新近发现的调节细胞生长和分化的TGF-β超家族。这一家族除TGF-β外，还有活化素（activins)、抑制素（inhibins)、缪勒氏管抑制质（Mullerian inhibitor substance,MIS)和骨形成蛋白（bone morpho-genetic proteins,BMPs
谱和抗菌作用以及各种临床药理学特性的抗生素。 一、抗菌机制、影响抗菌作用因素及细菌耐药性 （一）抗菌作用机制 各种β-内酰胺类抗生素的作用机制均相似，都能抑制胞壁粘肽合成酶，即青霉素结合蛋白（penicillin binding proteins，PBPs），从而阻碍细胞壁粘肽合成，使细菌胞壁缺损，菌体膨胀裂解（胞壁粘肽合成过程见三十七章）。除此之外，对细菌的致死效应还应包括触发细菌的自溶酶活性，缺乏自溶酶的突变株则表现出耐药性。哺乳动物无细胞壁，不受β
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