- ￥2400
- PLLABS
- 加拿大
- PL0402284
- 2025年07月16日
- WB: 1:100-500 IHC: 1:500-1000 ICC: 1:500-1000
- Rabbit
- Hu
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- 详细信息
- 技术资料
- 免疫原：
peptide corresponding to a sequence at the C-terminus of human Ku70.
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0402284
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500 IHC: 1:500-1000 ICC: 1:500-1000
- 浓度：
1mg/ml
- 靶点：
XRCC6
- 抗体英文名：
XRCC6 Antibody
- 抗体名：
XRCC6抗体
- 规格：
0.1ml
XRCC6 Antibody
Cat#：PL0402284
Isotype:Rabbit Polyclonal IgG
Immunogen：peptide corresponding to a sequence at the C-terminus of human Ku70.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
XRCC6(X-Ray Repair, Complementing Defective, In Chinese Hamster, 6), also called Ku70, G22P1 or TLAA, is a protein that in humans, is encoded by the XRCC6 gene. In addition, the XRCC6 gene encodes subunit p70 of the p70/p80 autoantigen which consists of 2 proteins of molecular mass of approximately 70,000 and 80,000 daltons that dimerize to form a 10 S DNA-binding complex. The XRCC6 gene is mapped to 22q13.2. XRCC6 and Mre11 are differentially expressed during meiosis. XRCC6 interacts with Baxa, a mediator of mitochondrial-dependent apoptosis. Disruption of both FANCC and XRCC6 suppressed sensitivity to crosslinking agents, diminished chromosome breaks, and reversed defective homologous recombination. Ku70 binds directly to free DNA ends, committing them to NHEJ repair.
Alternate Names：
5''-deoxyribose-5-phosphate lyase Ku70 antibody;5''-dRP lyase Ku70 antibody;70 kDa subunit of Ku antigen antibody;ATP dependent DNA helicase 2 subunit 1 antibody;ATP dependent DNA helicase II 70 kDa subunit antibody;ATP-dependent DNA helicase 2 subunit 1 antibody;CTC box binding factor 75 kDa subunit antibody.
Specificity Reaction：Hu
Application Notes:WB: 1:100-500 IHC: 1:500-1000 ICC: 1:500-1000
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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XRCC6 Antibody
￥2400
