peptide corresponding to a sequence at the N-terminus of human HIF-1-alpha.
亚型:
Rabbit Polyclonal IgG
形态:
液态
保存条件:
保存于-20℃
克隆性:
多克隆
标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种:
Hu, Mo, Rat
保质期:
按说明书条件可保存1-2年
抗原来源:
见详细说明资料
目录编号:
PL0401040
级别:
超纯
库存:
大量
供应商:
华拓生物
宿主:
Rabbit
应用范围:
WB: 1:100-500 IHC: 500-1000
浓度:
1mg/ml
靶点:
HIF-1α
抗体英文名:
HIF-1α Antibody
抗体名:
HIF-1α抗体
规格:
0.1ml
HIF-1α Antibody
Cat#:PL0401040
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the N-terminus of human HIF-1-alpha.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
HIF-1 alpha(Hypoxia-inducible factor 1 alpha,HIF1A) is a transcription factor that mediates cellular and systemic homeostatic responses to reduced availability in mammals, including angiogenesis, erythropoiesis and glycolysis. This gene was mapped to 14q21-q24. HIF-1 alpha transactivate genes required for energy metabolism and tissue perfusion and is necessary for embryonic development and tumor explant growth. HIF-1 alpha is over expressed during carcinogenesis, myocardial infarction and wound healing. It is crucial for the cellular response to hypoxia and is frequently over expressed in human cancers, resulting in the activation of genes essential for cell survival. HIF-1 alpha regulates the survival and function in the inflammatory microenvironment directly.
Alternate Names:
ARNT interacting protein antibody;Basic helix loop helix PAS protein MOP1 antibody;bHLHe78 antibody;Class E basic helix-loop-helix protein 78 antibody;HIF 1A antibody;HIF 1alpha antibody;HIF1 A antibody;HIF1 Alpha antibody;HIF1 antibody;HIF1-alpha antibody;HIF1A antibody;HIF1A_HUMAN antibody; Hypoxia inducible factor 1 alpha antibody;Hypoxia inducible factor 1 alpha isoform I.3 antibody;Hypoxia inducible factor 1 alpha subunit antibody;Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor antibody;Hypoxia inducible factor 1, alpha subunit(basic helix loop helix transcription factor) antibody;Hypoxia inducible factor1alpha antibody;Member of PAS protein 1 antibody;Member of the PAS Superfamily 1 antibody;MOP 1 antibody;MOP1 antibody;PAS domain-containing protein 8 antibody;PASD8 antibody.
Specificity Reaction:Hu, Mo, Rat
Application Notes:WB: 1:100-500 IHC: 500-1000
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.