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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
Histone Deacetylase 6 (HDAC6) (N-Term) 抗体
- 规格:
0.1ml/0.2ml
Histone Deacetylase 6 (HDAC6)
别名
CG6170, DHDAC2, DmHDAC2, Dmel\\CG6170, HDAC, HDAC2, dHDAC2, dHDAC6, dmHDA404, hdac6, MGC53140, wu:fc31d02, dsim_GLEANR_17355, DsimGD17207, GD17207, HDAC6, HD6, Hd6, Hdac5, Sfc6, mHDA2, ATHDA6, AXE1, H ... show more
抗原表位
其他选择 N-Term
适用
其他选择 犬, 大鼠, 小鼠, 牛, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb182371
产品细节 Histone Deacetylase 6 (HDAC6) (N-Term) 抗体
免疫原 Synthetic peptide directed towards the N terminal of human HDAC6
序列 VGLQGMDLNL EAEALAGTGL VLDEQLNEFH CLWDDSFPEG PERLHAIKEQ
预测反应 Horse : 100 %, Human : 100 %, Rabbit : 100 %, Bovine : 90 %, Rat : 90 %, Mouse : 80 %
产品特性 This is a rabbit polyclonal antibody against HDAC6. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
目标详细情况 Histone Deacetylase 6 (HDAC6) (N-Term) 抗体
别名 HDAC6
背景 Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
分子量 131 kDa
基因ID 10013
NCBI登录号 NM_006044
UniProt Q9BRX7
研究领域 Chromatin and Nuclear Signaling, Wnt, DNA/RNA, Transcription Factors
使用细节 Histone Deacetylase 6 (HDAC6) (N-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 1215 AA
限制 仅限研究用
贮存及处理 Histone Deacetylase 6 (HDAC6) (N-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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文献和实验Histone Acetylation and Deacetylation
residues in the N-terminal tails of the core histone can be post-translationally modified by acetylation of the ε-amino group. The dynamic equilibrium of core histone acetylation is established and maintained by histone acetyltransferase (HAT) and histone
去乙酰化的过程中,组蛋白去乙酰酶起着关键的作用。研究组蛋白去乙酰酶对于理解组蛋白乙酰化和去乙酰化如何调节基因转录有着重要的作用。为此CST推出了组蛋白去乙酰酶系列抗体。Catalog#Product DescriptionSourceApplications2062Histone Deacetylase1(HADC1) AntibodyRabbitW IP IHC IC2632Histone Deacetylase3(HADC3) AntibodyRabbitW IHC IC2072Histone
浅析染色质免疫沉淀(ChIP)技术在 DNA 与蛋白质相互作用研究中的重要性
, Y., et al., GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development,2007. 134(1): p. 189-98. [2] Rossi, V., et al., A maize histone deacetylase and retinoblastoma-related protein physically
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