Midline 1 (MID1) (C-Term) 抗体

Midline 1 (MID1) (C-Term) 抗体抗原
Midline 1 (MID1)
别名 61B3-R, DXHXS1141, Fxy, Trim18, bbbg1, fxy, gbbb1, midin, ogs1, osx, rnf59, trim18, xprf, znfxy, BBBG1, FXY, GBBB1, MIDIN, OGS1, OS, OSX, RNF59, TRIM18, XPRF, ZNFXY, Midline1
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 犬, 牛, 非洲爪蟾, 人, 斑马鱼, 小鸡
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb183065
产品细节 Midline 1 (MID1) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human MID1
序列 AINQAGSRSS EPGKLKTNSQ PFKLDPKSAH RKLKVSHDNL TVERDESSSK
预测反应 African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Zebrafish : 100 %
产品特性 This is a rabbit polyclonal antibody against MID1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
目标详细情况 Midline 1 (MID1) (C-Term) 抗体
别名 MID1
背景 MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing, however, the full length nature of two variants has not been determined.
分子量 75 kDa
基因ID 4281
NCBI登录号 NM_000381, NP_000372
UniProt O15344
研究领域 Proteolysis / Ubiquitin
使用细节 Midline 1 (MID1) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 667 AA
限制 仅限研究用
贮存及处理 Midline 1 (MID1) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C