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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
CD86 Molecule (CD86) 抗体 (PE)
- 规格:
0.1ml/0.2ml
CD86 Molecule (CD86)
别名 B7-2, B7, B7.2, B70, CLS1, Cd28l2, ETC-1, Ly-58, Ly58, MB7, MB7-2, TS/A-2, CD28LG2, LAB72
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (BU63)
标记
其他选择 PE
CD86 Molecule (CD86) 抗体 (PE)应用范围
其他选择 流式细胞分析技术(FACS)
Pubmed 找到1个引用
规格 100 tests
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号yb118807
产品细节
免疫原 Human peripheral blood lymphocytes. Spleen cells from immunised mice were fused with cells of the mouse P3.X63 Ag8653 myeloma cell line.
克隆位点 BU63
亚型 IgG1
特异性 This antibody recognises the CD86 antigen.
纯化方法 Affinity chromatography on Protein A
目标详细情况
别名 CD86
CD86 Molecule (CD86) 抗体 (PE)背景 CD86 is a cell surface protein expressed by activated B cells and monocytes. CD86 is also known as B7-2, and is the second ligand for CD28 and CTLA-4, and may have an important role in co-stimulation of T cells in the primary immune response.Synonyms: Activation B7-2 antigen, B7.2, B70, BU63, CD28LG2, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86
基因ID 942
NCBI登录号 NP_008820
UniProt P42081
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节
应用备注 Flow Cytometry: Neat-1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理
溶解方式 Restore with 1 mL distilled water.
浓度 1.0 mg/mL
缓冲液 PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
储存液 Sodium azide
CD86 Molecule (CD86) 抗体 (PE)注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 This product is photosensitive and should be protected from light
储存条件 4 °C
储存方法 Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
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文献和实验CD86 分子 CD86 常用单克隆抗体或代号: FUN- 1,BU63,GR65;(B7- 2) 主要表达细胞: Ba,M [B] 分子质量(kDa)和结构: gp80(IgSF) 功 能: CD28、CTLA- 4配体,提供T细胞共刺激信号 CD86 Summary: Costimulates IL-2 production and T cell proliferation
Topical Application of siRNA Targeting Cutaneous Dendritic Cells in Allergic Skin Disease
a crucial role in inducing immunity and tolerance. In our recent work, we have shown a successful treatment using CD86 siRNA targeting cutaneous DCs. A costimulatory molecule, CD86, is induced on DCs in situ after antigen uptake, and CD86
CD28 分子 CD28 常用单克隆抗体或代号: 9.3,4B10 主要表达细胞: Tsub, Ba,PC [T] 分子质量(kDa)和结构: gp44(IgSF)(同源二聚体) 功 能: 与CD80、CD86互为配体,提供T细胞共刺激信号 CD28 Cell adhesion molecule; co-receptor for B cell-T cell cooperation Promotes T cell activation
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