2型神经纤维瘤抗体

2型神经纤维瘤抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

2型神经纤维瘤抗体产品介绍

Ⅱ型神经纤维瘤(neurofibromatosisⅡ,NF2)又称merlin蛋白在细胞与细胞的信号传递中起着关键作用，可能与其它类型癌症也有关联。
Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility.
Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.
mol wt:65kDa
Other Aliases:
neurofibromatosis type 2; CAN; BANF; bilateral acoustic neuroma; moesin ezrin radixin like protein; Moesin ezrin radizin like protein; Neurofibromatosis 2; Neurofibromatosis2; Neurofibromin 2; Neurofibromin2; Schwannomerlin; NF 2; NF-2; SCH; Schwannomin

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