Serpin G1 / SERPING1 / C1IN抗体

Serpin G1 / SERPING1 / C1IN抗体产品信息

免疫原 :
Recombinant human SerpinG1 protein ( Catalog#10995-H08H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant human SerpinG1 ( rh SerpinG1 ; Catalog#10995-H08H ; NP_000053.2 ; Met 1 - Ala 500 ). SerpinG1 specific IgG was purified by human SerpinG1 affinity chromatography.
Serpin G1 / SERPING1 / C1IN抗体 Background
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine protease inhibitor protein. C1-INH is the largest member among the serpin class of proteins. Remarkably, C1-INH has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. The N-terminal domain is not essential for C1-INH to inhibit proteinases and has no similarity to other proteins. The main function of C1-INH is the inhibition of the complement system to prevent spontaneous activation. C1-INH is an acute phase protein and circulates in blood at levels of around 0.25 g/L, whose levels rise 2-fold during inflammation. C1-INH irreversibly binds to and inactivates C1r and C1s proteinases in the C1 complex of classical pathway of complement. C1-INH prevents the proteolytic cleavage of later complement components C4 and C2 by C1 and MBL. Although named after its complement inhibitory activity, C1-INH also inhibits proteinases of the fibrinolytic, clotting, and kinin pathways. Most notably, C1-INH is the most important physiological inhibitor of plasma kallikrein, fXIa and fXIIa.
Serpin G1 / SERPING1 / C1IN抗体相关产品如下：
hz-13304R GBP6G蛋白结合蛋白6体
hz-13306R GCAP1鸟苷酸环化酶激活蛋白1抗体
hz-13307R GCAP2鸟苷酸环化酶激活蛋白2抗体
hz-13308R GCAP3鸟苷酸环化酶激活蛋白3抗体
hz-13309R GCAT氨基丙酮合成酶抗体
hz-13310R GCC1高尔基体卷曲螺旋蛋白1抗体
hz-13311R GCC2高尔基体卷曲螺旋蛋白2抗体
hz-13312R GCDH戊二酰辅酶A脱氢酶抗体
hz-13313R GCHFRGTP环反馈调节蛋白抗体
hz-13314R GCM2绒毛膜特异性转录因子GCM2抗体
hz-13315R Gcn1l1广泛控制氨基酸合成1样蛋白1抗体
hz-13316R GCNT2β1-6 N-乙酰氨基葡萄糖转移酶2抗体
hz-13359R phospho-GIRK1 (Ser185)磷酸化G蛋白激活内向钾通道1抗体
hz-13360R GIT2G蛋白偶联受体激酶相互作用蛋白2抗体
hz-13362R GJA10间隙连接蛋白10抗体
hz-13363R GJA3间隙连结蛋白46/白内障相关蛋白抗体
hz-13364R GJA8间隙连结蛋白50/白内障相关蛋白抗体
hz-13365R GJC1间隙连结蛋白31.9抗体
hz-13366R GK2甘油激酶2抗体
hz-13369R GLB1β-半乳糖苷酶1/β-Gal/弹性蛋白受体1抗体
hz-13370R GLDC甘氨酸脱羧酶P蛋白抗体
hz-13371R GLE1核孔蛋白GLE1抗体
hz-13372R GLEPP1肾小球上皮蛋白1抗体
hz-13373R GLI4转录因子Gli4/锌指蛋白gli4抗体
hz-13374R Gliadin麦角蛋白抗体
hz-13375R GLIPR1L1胶质瘤发病相关蛋白1抗体
hz-13378R GLT25D1糖基转移酶25结构域1/前胶原半乳糖基转移酶1抗体
hz-13376R GLS2谷氨酰胺酰胺水解酶抗体
hz-13379R GLT25D2糖基转移酶25结构域2/前胶原半乳糖基转移酶2抗体
hz-13380R GLT28D1糖基转移酶28家族1抗体
hz-13381R GLT6D1糖基转移酶6结构1抗体
hz-13382R GLTSCR2胶质瘤抑癌候选基因2抗体
hz-13384R Phospho-Glucocorticoid Receptor (Ser226)磷酸化糖皮质激素受体抗体
hz-13388R GLUT6葡萄糖转运蛋白6抗体
hz-13385R Glucocorticoid Receptor beta糖皮质激素受体β抗体
hz-13386R Glucose 6 phosphatase 2胰岛葡萄糖6磷酸酶2抗体
hz-13387R Glucose Oxidase葡萄糖氧化酶抗体
hz-13389R Glucosidase 2 subunit beta葡萄糖苷酶2β/Glucosidase IIβ抗体