Serpin G1 / SERPING1 / C1IN抗体

Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine protease inhibitor protein. C1-INH is the largest member among the serpin class of proteins. Remarkably, C1-INH has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. The N-terminal domain is not essential for C1-INH to inhibit proteinases and has no similarity to other proteins. The main function of C1-INH is the inhibition of the complement system to prevent spontaneous activation. C1-INH is an acute phase protein and circulates in blood at levels of around 0.25 g/L, whose levels rise 2-fold during inflammation. C1-INH irreversibly binds to and inactivates C1r and C1s proteinases in the C1 complex of classical pathway of complement. C1-INH prevents the proteolytic cleavage of later complement components C4 and C2 by C1 and MBL. Although named after its complement inhibitory activity, C1-INH also inhibits proteinases of the fibrinolytic, clotting, and kinin pathways. Most notably, C1-INH is the most important physiological inhibitor of plasma kallikrein, fXIa and fXIIa.
Serpin G1 / SERPING1 / C1IN抗体相关产品如下：xy-9318R phospho-NEK9(Thr210)磷酸化丝氨酸/苏氨酸蛋白激酶NEK9抗体
xy-9319R NNF1R多胺调控因子1抗体
xy-9300R NNP1新型核蛋白质1抗体
xy-7080R Nucleolar protein 3核仁蛋白3抗体
xy-9625R NPAP1核孔蛋白1抗体
xy-4730R NADPH oxidase 4NADPH氧化酶4抗体
xy-9713R FAD24脂肪细胞分化因子24
xy-9468R Nebulette肌动蛋白结合蛋白Z盘状蛋白抗体
xy-9473R NFAT5活化T细胞核因子5蛋白抗体
xy-9474R phospho-NFAT5 (Ser1197)磷酸化活化T细胞核因子5蛋白抗体
xy-1373R Lipocalin 2脂质运载蛋白抗体
xy-1366R NF22型神经纤维瘤抗体
xy-8513R NIR1膜相关磷脂转运蛋白抗体
xy-0903R Natrexone纳曲酮抗体IgG
xy-3297R Phospho-NDRG1 (Ser330)磷酸化分化相关基因NDRG1抗体
xy-3298R Phospho-NDRG1 (Thr346)磷酸化分化相关基因NDRG1抗体
xy-3506R NEDD4L泛素连接酶NEDD4-2抗体
xy-3291R Phospho-NF2(Ser518)磷酸化2型神经纤维瘤抗体
xy-3302R Phospho-NMDAR1(Ser896)磷酸化谷氨酸受体1抗体
xy-3903R Phospho-NMDAR1 (Ser897)磷酸化谷氨酸受体1抗体
xy-11214R Nfasc186 神经束蛋白186抗体
xy-3299R Phospho-NEDD4L (Ser342)磷酸化泛素连接酶NEDD4-2抗体
xy-3300R Phospho-NFKB1 (Ser927)磷酸化细胞核因子p50/k基因结合核因子抗体
xy-3301R Phospho-NMDAR1 (Ser890)磷酸化谷氨酸受体1抗体
xy-3561R KAT13C类固醇受体激活蛋白2抗体
xy-0829R Nanog胚胎干细胞关键蛋白抗体
xy-1052R NAP1L1核小体组装蛋白1抗体
xy-1172R N-cadherinN-钙粘附分子抗体
xy-0224R NCoR1核受体辅助抑制因子1抗体
xy-0513R Nephrin肾小球细胞粘附分子受体抗体
xy-0006R Nestin巢蛋白/神经上皮干细胞蛋白抗体
xy-0008R Nestin巢蛋白/神经上皮干细胞蛋白抗体
xy-0268R Neurobeachin蛋白激酶锚定蛋白抗体
xy-11317R Neuroserpin丝氨酸或半胱氨酸蛋白水解酶抑制蛋白1抗体
xy-4800R NG2黑色素瘤硫酸软骨素蛋白多糖抗体
xy-11181R Neuroligin 3突触细胞粘附分子3抗体
xy-11323R Neuroglycan C跨膜硫酸软骨素蛋白聚糖C抗体
xy-11324R Nova1神经肿瘤Nova1抗原抗体
xy-9558R NTALB淋巴细胞链接激活蛋白抗体
xy-11193R NSMase2中性鞘磷脂2抗体
xy-11202R NR2E1核受体蛋白NR2E1抗体
xy-11171R NXPH2神经外营养蛋白2抗体