ADAM12 / MLTN抗体

ADAM12 / MLTN抗体产品信息

免疫原 :
Recombinant human ADAM12 protein ( Catalog#10896-H08H )
抗体类型: Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant human ADAM12 / MLTN extracellular domain ( rh ADAM12 ; Catalog#10896-H08H ; NP_003465.3 ; Met 1 - Ser 513 ). ADAM12 specific IgG was purified by human ADAM12 affinity chromatography.
ADAM12 / MLTN抗体背景综述
Disintegrin and metalloproteinase domain-containing protein 12, also known as ADAM12 and Meltrin alpha, is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 is an active metalloprotease, and has been implicated in insulin-like growth factor (IGF) receptor signaling, through cleavage of IGF-binding proteins, and in epidermal growth factor receptor (EGFR) pathways, via ectodomain shedding of membrane-tethered EGFR ligands. ADAM12 contains one disintegrin domain, one EGF-like domain and one peptidase M12B domain. It is involved in skeletal muscle regeneration, specifically at the onset of cell fusion. It is also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. ADAM12 possesses extracellular metalloprotease and cell-binding functions, as well as intracellular signaling capacities. Interest in ADAM12 has increased because its expression is related to tumor progression and it is a potential biomarker for breast cancer.
ADAM12 / MLTN抗体相关产品如下：
hz-8286R DYDC1DYDC1蛋白抗体
hz-8287R Dihydropyrimidinase二氢嘧啶抗体
hz-8249R DCAKD脱磷酸辅酶Ａ结构域蛋白抗体
hz-8250R DCST1DCST1蛋白抗体
hz-8251R DCUN1D4DCUN1D4蛋白抗体
hz-8259R DHPS脱氧辅合酶蛋白抗体
hz-8266R DHRS4L2短链脱氢酶/还原酶家族4样2蛋白抗体
hz-8252R DDRGK1DDRGK1蛋白抗体
hz-8253R DENND2ADENND2A蛋白抗体
hz-8254R DENND1BDENND1B蛋白抗体
hz-8255R DEPTORDEPTOR蛋白抗体
hz-8256R DIAPH1耳聋常染色体显性遗传相关蛋白1抗体
hz-7859R DHRS9短链脱氢酶/还原酶家族9抗体
hz-8261R DHRS13短链脱氢还原酶13抗体
hz-8262R DHRS7视网膜短链脱氢酶/还原酶家族7抗体
hz-8263R DHRSX短链脱氢酶/还原酶家族X抗体
hz-8264R DHRS4短链脱氢酶/还原酶家族4抗体
hz-8278R DIRC2干扰肾细胞癌蛋白2抗体
hz-8258R DGCR2DGCR2蛋白抗体
hz-8265R DHRS7C短链脱氢酶/还原酶家族7C抗体
hz-6961R ASMTY松果体N甲基乙酰羟色胺抗体
hz-8260R DHPS1短链脱氢还原酶1抗体
hz-8280R DNAJC7DNAJC7蛋白抗体
hz-8281R DNMBP动力结合蛋白DNMBP抗体
hz-8282R DPH2白喉酰胺生物合成样蛋白2抗体
hz-7860R DLL3Notch信号通路Delta样配体3抗体
hz-7836R DCTN2动力蛋白激活蛋白2抗体
hz-11657R DOCK3视神经细胞相关蛋白/早老素结合蛋白抗体
hz-6944R DHX32DHX螺旋酶抗体
hz-11588R DISP2转运蛋白DISP2抗体
hz-7823R DNA polymerase subunit IIDNA聚合酶α2抗体
hz-13000R DHRS7B短链脱氢酶/还原酶家族7B抗体
hz-7795R DPEP3膜二肽酶3抗体
hz-7797R DUSP13双特异性磷酸酶13抗体
hz-10015R DIM-7DIM-7蛋白抗体
hz-6697R DICER1核糖核酸酶Dicer抗体
hz-5834R DCBLD2内皮细胞和平滑肌细胞衍生的神经纤毛蛋白抗体
hz-2835R ASB2含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族2抗体
hz-6641R DNA Ligase 1DNA连接酶1抗体
hz-5910R DHHDHH蛋白抗体
hz-6608R DDCTD型多巴色素脱羧酶
hz-6166R DNA polymerase alphaDNA聚合酶α抗体
hz-9665R MREGMREG蛋白抗体
hz-6163R DIRAS1RAS相关抑细胞生长蛋白1抗体
hz-9667R DENND2CMAP激酶激活死亡域蛋白2C抗体
hz-3902R Dio3甲状腺素5'脱碘酶3抗体
hz-3624R Delta Opioid ReceptorD型受体抗体