Cynomolgus CD200RLa抗体

Cynomolgus CD200RLa抗体产品信息

免疫原 :
Recombinant cynomolgus CD200RLa protein ( Catalog# 11576-C08H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant cynomolgus CD200RLa ( rC CD200RLa ; Catalog# 11576-C08H ; Met 1 - Leu 240 ). CD200RLa specific IgG was purified by cynomolgus CD200RLa affinity chromatography
Cynomolgus CD200RLa抗体背景综述
Cynomolgus CD200 cell surface glycoprotein receptor-like a, also known as CD200RLa, is a member of the CD200R family. CD200 is a transmembrane protein delivering immunoregulatory signals after engagement of CD200R. A family of CD200Rs exist ( CD200R1, CD200R2, CD200R3, CD200R4 ) with different tissue expression and functional activity. CD200 (OX2) is a cell surface glycoprotein that interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. CD200 gave negligible binding to the activating receptors, CD200RLa, CD200RLb, and CD200RLc, by direct analysis at the protein level using recombinant monomeric and dimeric fusion proteins or to CD200RLa and CD200RLb when expressed at the cell surface.
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