CD95 / Fas / TNFRSF6抗体

CD95 / Fas / TNFRSF6抗体产品信息

免疫原 :
Recombinant human CD95 protein ( Catalog#10217-H08H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant human CD95 ( rh CD95 ; Catalog#10217-H08H ; NP_000034.1 ; Met 1- Asn 173 ). CD95 specific IgG was purified by human CD95 affinity chromatography
CD95 / Fas / TNFRSF6抗体背景综述
Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the tumor necrosis factor (TNF) / nerve growth factor (NGF) receptor superfamily. Fas is highly expressed on the surface of a number of cell types including epithelial cells, hepatocytes, activated mature lymphocytes and other tumor cells. This receptor contains a death domain and has been shown to play a central role in the physiological regulation of programmed cell death (PCD, apoptosis) upon ligation of Fas ligand (Fas-L). This Fas receptor has been reported to be involved in the activation of NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and the alternate pathways for CTL-mediated cytotoxicity. Accordingly, this protein is implicated in the pathogenesis of various malignancies and diseases of the immune system. Multiple Fas isoforms are derived from alternative spliced transcript variants, and among which, a soluble form lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoforms.
CD95 / Fas / TNFRSF6抗体相关产品如下：
hz-0101R PKM2丙酮酸激酶-M2抗体
hz-11140R PCDHB7原钙粘蛋白β7抗体
hz-1927R uPA Receptor尿激酶型纤溶酶原激活因子受体抗体
hz-1861R PAX5配对盒基因5抗体
hz-1870R PEG3PEG3蛋白抗体
hz-1872R PIRH2泛素连接酶抗体
hz-1865R Parkin帕金蛋白抗体
hz-1867R PD-1程序性死亡1抗体
hz-1874R PRDX3过氧化还原酶3抗体
hz-1879R PSAP前列腺酸性磷酸酶抗体
hz-3537R PRAS40蛋白激酶AKT底物1抗体
hz-3518R PAK1p21激活激酶1抗体
hz-0338R HGV Polyprotein庚型肝炎病毒多聚蛋白抗体
hz-0273R PBEF1内脂素/内脏脂肪素/前B细胞克隆增强因子1抗体
hz-0056R Proinsulin胰岛素原抗体
hz-4734R Podoplanin Protein平足蛋白gp36/淋巴管内皮细胞蛋白抗体
hz-1760R ENPP1核苷酸内焦磷酸酶/磷酸二酯酶1抗体
hz-11930R PTF1A胰腺特异转录因子PTF1A抗体
hz-11931R PTPRS蛋白酪氨酸磷酸酶PTPσ抗体
hz-11933R Pet1ETS结构域转录因子FEV抗体
hz-11934R Plexin A3神经丛蛋白A3抗体
hz-10167R phospho-PTPN6(Tyr564)磷酸化蛋白酪氨酸磷酸酶1C抗体
hz-6428R PPP4C丝氨酸/苏氨酸蛋白磷酸酶4C抗体
hz-11923R PASD5神经元PAS结构域蛋白5抗体
hz-11924R PCPTP1蛋白酪氨酸磷酸酶受体PCPTP1抗体
hz-11925R PHYHIP植烷酰辅酶A羟化酶2相互作用蛋白抗体
hz-11926R PNMA1旁瘤抗原MA1抗体
hz-11947R POU3F3大脑蛋白1抗体
hz-11928R PTBP2核糖核酸结合蛋白2抗体
hz-4888R Phospho-PPAR Gamma (ser273)磷酸化过氧化酶活化增生受体γ抗体 PPARγ
hz-11681R Presenilin 1 + 2早老素蛋白1+2抗体
hz-10043M PRRSV猪蓝耳病病毒抗体
hz-6472R Phospholipase C beta 2磷酯酶Cβ2抗体
hz-8300R Peroxiredoxin 2硫氧还蛋白过氧化物酶Ⅱ/巯基抗氧化蛋白抗体
hz-6423R PI3 Kinase p110 beta磷脂酰肌醇激酶（PI3Kβ）抗体
hz-6918R PPAPDC3磷脂酸磷酸酶2结构域3抗体
hz-6904R PRC1胞质分裂调控蛋白1抗体
hz-6419R phospho-PP2A alpha+beta(Tyr307)磷酸化蛋白磷酸酶2A（PP2Aα）抗体
hz-8062R PLEKHM1石骨症相关蛋白PLEKHM1抗体
hz-8063R PLEKHM2血小板白细胞C激酶底物同源结构域M2抗体
hz-8064R PLEKHM3血小板白细胞C激酶底物同源结构域M3抗体
hz-2138R PARP多腺苷二磷酸多聚酶抗体(N端)
hz-11471R PTPRD酪氨酸磷酸酶PTPδ抗体 蛋白酪氨酸磷酸酶D受体抗体
hz-11123R PCDHA10/CNRN8钙粘蛋白相关神经受体8抗体
hz-11112R PCDH18原钙粘附蛋白18抗体
hz-11113R PCDH20原钙粘附蛋白20抗体
hz-11114R PCDH8原钙粘附蛋白8抗体
hz-6371R Protamine 2鱼精蛋白2抗体
hz-6853R PIWIL4piwi样4蛋白抗体
hz-6348R PIWIL3piwi样3蛋白抗体