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文献和实验Herpes Simplex Amplicon Vectors
The key fundamental problem for effective gene therapy remains gene delivery. Gene therapy has achieved some modest success in animal and human experiments (1 –7 ). However, effective gene delivery remains the chief obstacle. Herpes simplex
Use of Defective Herpes-Derived Plasmid Vectors
Genetic intervention is becoming increasingly useful in elucidating the molecular basis of various biological processes, including those of the brain. Many genes have now been isolated which encode key regulatory molecules such as signal
Generation of Recombinant Herpes Simplex Virus Ampiicons
The herpes simplex virus type 1 (HSV-1) amphcon has been developed as a novel eukaryotic expression vector, which contains an HSV-1 ori for DNA replication and a pac signal for cleaving/packaging genomes into viral
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