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- 2025年07月11日
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- 技术资料
- 保存条件：
常温，避光
- 克隆性：
单克隆
- 抗体名：
Ki-67抗体
免疫原 :
A synthetic peptide corresponding to the sequence of the Human Ki-67.
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, a synthetic peptide corresponding to the sequence of the Human Ki-67, and purified by antigen affinity chromatography.
Ki-67抗体 Background
The Ki-67 protein is a nuclear and nucleolar protein, which is tightly associated with somatic cell proliferation. Antibodies raised against the human Ki-67 protein paved the way for the immunohistological assessment of cell proliferation, particularly useful in numerous studies on the prognostic value of cell growth in clinical samples of human neoplasms. Ki-67 protein expression is an absolute requirement for progression through the cell-division cycle. Recently, Ki-67 is proved be an independent prognostic factor for disease-free survival (HR 1.05-1.72) in multivariate analyses studies using samples from randomized clinical trials with secondary central analysis of the biomarker. Ki-67 was not found to be predictive for long-term follow-up after chemotherapy. Nevertheless, high KI-67 was found to be associated with immediate pathological complete response in the neoadjuvant setting, with an LOE of II-B. KI-67 could be considered as a prognostic biomarker for therapeutic decision.
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文献和实验baibai17 今天开题，导师问了个问题：ki67为什么叫ki67？当场傻住······恳请各位老师指教！谢谢。 keavin521 The Ki-67 protein was originally defined by the prototype monoclonal antibody Ki-67 (Gerdes et al., 1983),which was generated by immunizing mice
Flow Cytometric Detection of Proliferation-Associated Antigens, PCNA and Ki-67
The rapid evolution of monoclonal antibody (MAb) technology has resulted in an ever-growing repertoire of proteins becoming accessible for study using immunohistochemical techniques. Nuclear antigens represent a class of proteins
Immunohistochemistry of p53, Bcl-2, and Ki-67 as Predictors of Chemosensitivity
Chemosensitivity is affected by molecular biological factors, including factors related to the induction of apoptosis and the activity of proliferation. We analyzed immunohistochemically the expression of p53, Bcl-2, and Ki-67 in various
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