免疫原 :
Recombinant Human CLPS / Colipase protein (Catalog#13631-H08B)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Human CLPS / Colipase (rh CLPS / Colipase; Catalog#13631-H08B; P04118; Met1-Gln112). CLPS / Colipase specific IgG was purified by Human CLPS / Colipase affinity chromatography.
CLPS / Colipase抗体Background
Colipase is a member of the colipase family. It is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase is a small protein with five conserved disulphide bonds. Structural analogies have been recognised between a developmental protein, the pancreatic lipase C-terminal domain, the N-terminal domains of lipoxygenases and the C-terminal domain of alpha-toxin. Colipase is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilising as active conformation and considerably increasing the overall hydrophobic binding site. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
CLPS / Colipase抗体相关产品如下:
hz-5208R phospho-ATG4C(Ser166)磷酸化自噬相关蛋白4C抗体
hz-5206R phospho-ATG16A(Ser213)磷酸化自噬相关蛋白16A抗体
hz-5209R phospho-AKT3 (Ser472)磷酸化蛋白激酶AKT3抗体
hz-5211R phospho-ADRB2 (Ser261)磷酸化肾上腺素能受体β2抗体
hz-5214R phospho-AQP2(Ser261)磷酸化水通道蛋白2抗体
hz-5204R phospho-ATG3 (Tyr18)磷酸化自噬相关蛋白3抗体
hz-4026R ALDOB醛缩酶2抗体
hz-3975R AMY2A胰腺α淀粉酶抗体
hz-7961R ANKRD11锚蛋白重复结构域蛋白11抗体
hz-8440R phospho-c-ABL1+2 (Tyr393+429)磷酸化非受体酪氨酸激酶c-Abl抗体
hz-8449R phospho-ATF2 (Thr53)磷酸化活化复制因子2抗体
hz-5026R AKR1D1醛固酮还原酶家族1成员D1抗体
hz-5027R ARP4肝血管生成素相关蛋白抗体
hz-5028R ABHD5自水解酶结构域5蛋白抗体
hz-5031R ACOT8酰基辅酶A硫酯酶8
hz-5032R Agpat2溶血磷脂酸酰基转移酶β抗体
hz-10084R AFP4bAFP4b蛋白抗体
hz-5036R APOC2载脂蛋白C2抗体
hz-5035R Apolipoprotein A V载脂蛋白A5抗体
hz-5034R APOA2载脂蛋白A2抗体
hz-5033R AGPAT4溶血磷脂酸酰基转移酶D抗体
hz-5039R APOE3载脂蛋白E3抗体
hz-5985R ABI3ABI基因家族2抗体
hz-5983R AARE氧化蛋白质水解酶
hz-2390R Aconitase 2铁调节蛋白2抗体
hz-5106R ALDH1乙醛脱氢酶1型抗体
hz-10082R AFP4aAFP4a蛋白抗体
hz-9296R ARHGAP32Rho GTP酶激活蛋白32抗体
hz-9886R Adropin能量平衡相关蛋白抗体
hz-4696R AEV polyprotein禽脑脊髓炎病毒AEV抗体
hz-3924R ADCY7腺苷酸环化酶7抗体
hz-3921R ADCY4腺苷酸环化酶4抗体
hz-3911R AMPK gamma 1腺苷酸活化蛋白激酶γ1抗体
hz-3914R AANAT芳香胺N-乙酰化转移酶抗体
hz-3925R ADCY8腺苷酸环化酶8抗体
hz-3916R ADCY10腺苷酸环化酶10抗体
hz-3922R ADCY5腺苷酸环化酶5抗体
hz-3923R ADCY6腺苷酸环化酶6抗体
hz-3926R ADCY9腺苷酸环化酶9抗体
hz-3928R ALS2CR2肌萎缩侧索硬化症相关蛋白2(2号染色体)抗体
hz-3929R ATP citrate lyase三磷酸腺柠檬酸裂解酶抗体
hz-6172R APBB1 interacting protein 1β淀粉样蛋白前体结合蛋白B-1抗体
hz-4559R alpha Adducin内收蛋白a1抗体
hz-6188R Alpha 2 antiplasmin α2纤溶酶色素上皮衍生因子抗体
hz-5917R Annexin A7膜粘连蛋白7抗体
hz-4259R APH1a早老素γ分泌酶抗体
hz-4255R ATP1A1钠钾ATP酶蛋白a1抗体
hz-4202R GEF H1Rho鸟苷酸交换因子2抗体
hz-5704R phospho-GEF H1(Ser885)磷酸化Rho鸟苷酸交换因子2抗体
hz-4204R ADAM9去整合素样金属蛋白酶9抗体
hz-5831R ANKHD1艾滋病病毒制约锚定蛋白抗体
hz-4288R Adenylate cyclase 1腺苷酸环化酶1抗体