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文献和实验Immunoassays for Collagenase-Mediated Cleavage of Type I and II Collagens
This chapter describes the production and characterization of antibodies raised against neoepitopes in collagenase-cleaved collagen. It also details the development, validation, and use of immunoassays using such antibodies to measure
Immunoassay for Collagenase-Mediated Cleavage of Types I and II Collagens
-1 (collage-nase-1 or fibroblast/interstitial collagenase), MMP-8 (collagenase-2 or neutrophil collagenase), and MMP-13 (collagenase-3). All three, in addition to a membrane-type MMP (MT-MMP) designated MT1-MMP (MMP-14), cleave the collagen molecules to yield
-1 Collagenase-1 Collagens I, II, III, VI, X, gelatins, aggrecan, entactin (154–158) MMP-2 72
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