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- 文献和实验
- 技术资料
- 保存条件:
常温,避光
- 克隆性:
单克隆
- 抗体名:
Human Serum Albumin Antibody
Immunogen :
Human Serum Albumin / HSA
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID :
101
Ig Type :
Rabbit IgG
Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :
This antibody was obtained from a rabbit immunized with purified Human Serum Albumin]
Human Serum Albumin Antibody Background
Human Serum Albumin is produced in the liver and constitutes the biggest part of the human blood serum protein. Serum albumin is the main protein of plasma which belongs to the ALB/AFP/VDB family. It has a good binding capacity for water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Serum albumin functions as the major zinc transporter in plasma and typically binds about 80% of all plasma zinc. Besides zinc, it also transports hormones, fatty acids, and other compounds. As a negative acute-phase protein, serum albumin is lowly expressed in inflammatory states, and thus can be taken as a marker in inflammatory states. Serum albumin also can maintains oncotic pressure and prevents photodegradation of folic acid. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
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文献和实验Screening Major Binding Sites on Human Serum Albumin by Affinity Capillary Electrophoresis
A screening method is described for determining whether a drug or small solute has significant interactions at the two major binding sites on human serum albumin (HSA). This method uses affinity capillary electrophoresis (ACE) to perform
Serum is a readily available source for diagnostic assays, but the identification of disease-specific serum biomarkers has been impeded by the dominance of human serum albumin (HSA) and immunoglobulin G (IgG) in the serum proteome
Peptide Microarrays for Serum Antibody Diagnostics
to capture antigen-specific antibodies from serum samples; however, both the biologically active surface display of peptides and the establishment of a solidly performing peptide microarray immunoassay are often troublesome in detail. The following protocols
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