FSTL1 / FRP抗体

FSTL1 / FRP抗体产品信息免疫原 : Recombinant human FSTL1 protein ( Catalog#10924-H08H )

抗体类型: Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG

缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, human cell-derived, recombinant human FSTL1 / FRP ( rh FSTL1 ; Catalog#10924-H08H ; NP_009016.1 ; Met 1- Ile 308 ). Total IgG was purified by Protein A affinity chromatography.
FSTL1 / FRP抗体背景综述
Follistatin-like 1, also known as FSTL1, is an activin-binding protein with similarity to follistatin. It contains an FS module, a follistatin-like sequence containing ten conserved cysteine residues, two EF-hand domains, a Kazal-like domain and a VWFC domain. This heparin binding protein is involved in the BMP signaling pathway, and may modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 is thus suggested as a regulator of early mesoderm patterning, somitogenesis, myogenesis and neural development. FSTL1 is ubiquitously expressed in the majority of tissues in adult, with strongly expressed level in the mesenchymal component and excluded from the epithelium. In addition, this protein is thought to be an autoantigen associated with rheumatoid arthritis.
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