C7 / Complement component 7抗体

C7 / Complement component 7抗体产品信息免疫原 : Recombinant Human C7 / Complement component 7 protein (Catalog#13848-H08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Human C7 / Complement component 7 (rh C7 / Complement component 7; Catalog#13848-H08H; P10643; Met1-Gln843). Total IgG was purified by Protein A affinity chromatography.
C7 / Complement component 7抗体 Background
Complement component 7 is a member of the complement C6/C7/C8/C9 family. It contains 1 EGF-like domain, 1 LDL-receptor class A domain, 1 MACPF domain, 2 Sushi (CCP/SCR) domains and 2 TSP type-1 domains. As a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. As a constituent of MAC, it plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Complement component 7 serves as a membrane anchor. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
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