CFHR2 / FHR2 / HFL3抗体

CFHR2 / FHR2 / HFL3抗体产品信息免疫原 : Recombinant Human CFHR2 / FHR2 / HFL3 protein (Catalog#13920-H08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Human CFHR2 / FHR2 / HFL3 (rh CFHR2 / FHR2 / HFL3; Catalog#13920-H08H; P36980-1; Met1-Lys270). Total IgG was purified by Protein A affinity chromatography.
CFHR2 / FHR2 / HFL3抗体 Background
CFHR2 is a member of the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. It was identified as novel ligands for both borrelial proteins by employing MALDI-TOF. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.
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