MAPK1 / ERK2抗体

MAPK1 / ERK2抗体产品信息免疫原 : Recombinant Mouse MAPK1 / ERK2 protein (Catalog#50445-M20B)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Mouse MAPK1 / ERK2 (rM MAPK1 / ERK2; Catalog#50445-M20B; P63085; Met1-Ser358). Total IgG was purified by Protein A affinity chromatography.
MAPK1 / ERK2抗体 Background
Mitogen-activated protein kinase 1, also known as Extracellular signal-regulated kinase 2, ERK-2, and MAPK1, is a member of the protein kinase superfamily and MAP kinase subfamily. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. MKP-3 is a dual specificity phosphatase exclusively specific to MAPK1 for its substrate recognition and dephosphorylating activity. The activation of MAPK1 requires its phosphorylation by upstream kinases. Upon activation, MAPK1 translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. MAPK1 is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. MAPK1 acts as a transcriptional repressor which represses the expression of interferon gamma-induced genes. Transcriptional activity is independent of kinase activity.
MAPK1 / ERK2抗体相关产品如下：xy-3214R Phospho-HER2(Tyr1248)磷酸化HER2受体抗体
xy-2811R HDAC6组蛋白去乙酰化酶6抗体
xy-3215R phospho-HDAC6 (Ser22)磷酸化组蛋白去乙酰化酶6抗体
xy-2890R HDAC7组蛋白去乙酰化酶7抗体
xy-3216R phospho-HDAC7 (Ser358)磷酸化组蛋白去乙酰化酶7抗体
xy-2891R HDAC8组蛋白去乙酰化酶8抗体
xy-3184R Phospho-HER4 (Tyr984)磷酸化HER4抗体
xy-6458R HARS组氨酸tRNA连接酶抗体
xy-4529R NDV HN protein鸡新城疫血凝素－神经氨酸酶抗体
xy-1387R HSP105热休克蛋白105抗体
xy-1405R HNF1肝细胞核因子1α抗体
xy-1407R HIF-1 beta缺氧诱导因子1β /HIF-1β抗体
xy-1409R HSTF2热休克转录因子2抗体
xy-0966R HA tagHA tag标签抗体
xy-9066R HIG1缺氧诱导基因1蛋白抗体
xym-2026M HCG alpha(4A8)人绒毛膜促性腺激素α 亚基单抗
xym-2024M HBsAg(H2F4)人乙型肝炎表面抗原单克隆抗体（检测）
xym-2022M HBeAg (2E9)人乙型肝炎e抗原单克隆（包被）抗体
xym-2023M HBeAg(2E6)人乙型肝炎e抗原单克隆（检测）抗体
xym-2118M hHb(H5A3)小鼠抗人血红蛋白单克隆抗体
xy-2001R H1N1 Hemagglutinin 1甲型流感病毒血凝素抗体
xy-3213R Phospho-HER2(Tyr1112)磷酸化HER2受体抗体
xy-2809R HDAC4组蛋白去乙酰化酶4抗体
xy-3212R Phospho-HER2 (Tyr1221 + Tyr1222)磷酸化HER2受体抗体
xy-3127R phospho-HDAC8 (Ser39)磷酸化组蛋白去乙酰化酶8抗体
xy-1198R HLA-DRHLA-DR抗体
xy-0752R HLA G人类白细胞抗原G抗体
xy-0556R HMGA2高迁移率族蛋白A2抗体
xy-0664R HMGB1高迁移率族蛋白B1抗体
xy-1238R HO-2血红素氧合酶2抗体
xy-0394R HOXc8HOXc8抗体
xy-1071R HRAS原癌基因H-ras抗体
xy-0191R HSP60热休克蛋白-60抗体
xy-0126R HSP70热休克蛋白-70抗体
xy-0696R HSP90 alpha热休克蛋白90α抗体