- 询价
- Abcam
- 中国/美国/德国
- xy10445-MM02-F
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
常温，避光
- 克隆性：
单克隆
- 抗体名：
FLT3 / CD135 / FLK2抗体
Reagents : FITC-conjugated mouse monoclonal antibody
Clone ID : 02
抗体宿主 : Mouse IgG1
Concentration : 5 μl/Test, 0.2 mg/ml
缓冲液 : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 : This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FLT3 / CD135 / FLK2 (rh FLT3 / CD135 / FLK2; Catalog#10445-H08H; NP_004110.2; Met 1-Asn 541) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
FLT3 / CD135 / FLK2抗体 Background
FL cytokine receptor, also known as tyrosine-protein kinase receptor FLT3, Stem cell tyrosine kinase 1, STK-1, FLT3 and CD135, is a single-pass type I membrane protein. CD135 belongs to theprotein kinase superfamily and the CSF-1/PDGF receptor subfamily. It contains oneIg-like C2-type domain and oneprotein kinase domain. CD135 is an important cell surface marker used to identify certain types of hematopoietic progenitors in thebone marrow. Specifically,multipotent progenitors (MPP) andcommon lymphoid progenitors (CLP) express surface CD135 at high levels. This marker is therefore used to differentiatehematopoietic stem cells (HSC), which are CD135 negative, from MPPs, which are CD135 positive. Signaling through CD135 plays a role in cell survival, proliferation, and differentiation. CD135 is also important forlymphocyte (B cellandT cell) development, but not for the development of other blood cells (myeloiddevelopment). Identified as a proto-oncogene, the mutations of FLTS gene are associated with certain carcinomas.
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文献和实验Gene Therapy of X-Linked Severe Combined Immunodeficiency
to transduce ex vivo the CD34+cells of patients. This gene therapy protocol is currently being applied and the encouraging preliminary results published (1 ). The success of this protocol could be mainly attributed to the physiopathology of the SCID-X1 disease
x2值表 n＇ P 0.995 0.990 0.975 0.950
HIV的生物学标志之X4病毒株是检验技师考试中所包含的内容。医学教育网收集整理了部分相关信息供学员参考。 10月15日出版的《传染病杂志》上，一篇文章报道，HIV-1亚型B变异通过CXCR4（X4病毒）感染细胞，经常出现CD4+T细胞数量高，可能会导致晚期HIV-1感染过程中T细胞数量快速减少。 报道叙述了美国研究者进行的一项分析研究，他们的资料来自多中心艾滋病群体研究（MACS），这是一项几个主要城区近七千同性恋男性参加的纵向研究。因为样本选择接近流行
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