Semaphorin 6A / SEMA6A抗体

Semaphorin 6A / SEMA6A抗体产品信息免疫原 : Recombinant Human Semaphorin 6A / SEMA6A protein (Catalog#11189-H08H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 : 001

抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was obtained from a rabbit immunized with purified, recombinant Human Semaphorin 6A / SEMA6A (rh Semaphorin 6A / SEMA6A; Catalog#11189-H08H; NP_065847.1; Met1-Thr649).
Semaphorin 6A / SEMA6A抗体 Background
Semaphorin-6A, also known as Semaphorin VIA and SEMA6A, is a single-pass type I membrane protein which belongs to thesemaphorin family. Semaphorin-6A / SEMA6A contains onePSI domain and oneSema domain. Semaphorin-6A / SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation. Semaphorins are secreted, transmembrane, and GPI-linked proteins, defined by cysteine-rich semaphorin protein domains, that have important roles in a variety of tissues. Humans have 20 semaphorins, Drosophila has five, and two are known from DNA viruses. Semaphorins are found in nematodes and crustaceans but not in non-animals. They are grouped into eight classes on the basis of phylogenetic tree analyses and the presence of additional protein motifs. Semaphorins have been implicated in diverse developmental processes such as axon guidance during nervous system development and regulation of cell migration.
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