ICOS Ligand / B7-H2 / ICOSLG抗体

ICOS Ligand / B7-H2 / ICOSLG抗体产品信息
免疫原 : Recombinant Human ICOS Ligand / B7-H2 / ICOSLG protein (Catalog#11559-H08H)
Reagents : FITC-conjugated rabbit monoclonal antibody
Clone ID :101
抗体宿主 : Rabbit IgG
Concentration : 10 μl/Test, 0.1 mg/ml
缓冲液 : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 : This antibody was obtained from a rabbit immunized with purified, recombinant Human ICOS Ligand / B7-H2 / ICOSLG (rh ICOS Ligand / B7-H2 / ICOSLG; Catalog#11559-H08H; NP_056074.1; Met1-Ser258) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
ICOS Ligand / B7-H2 / ICOSLG抗体 Background
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. Present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. ICOSL constructs lacking either the IgC or IgV domain demonstrates that receptor binding is mediated solely by the IgV domain but requires the IgC domain for maintaining the structural integrity of the protein. The receptor binding site on ICOSL is constituted chiefly by aromatic / hydrophobic residues.
ICOS Ligand / B7-H2 / ICOSLG抗体相关产品如下：xy-0294xy-xyy7 Goat IgG/Cy7荧光素Cy7标记羊IgG(细胞流式同型对照)
xy-0293xy-xyy7 Rat IgG/Cy7荧光素Cy7标记大鼠IgG(细胞流式同型对照)
xy-0295xy-A555 Rabbit IgG/Alexa Fluor 555Alexa Fluor 555标记兔IgG(细胞流式同型对照)
xy-0366R-xyE Rb Anti-FITC/PE荧光素PE标记兔抗FITC
xy-0360G-xyE Goat Anti-human IgA/PE荧光素PE标记羊抗人IgA
xy-0312xy-xyE Avidin/PE荧光素PE标记亲合素
xy-0362xy-xyE Protein A/PEPE标记蛋白A
xy-0296xy-xyE Mouse IgG/PE荧光素PE标记小鼠IgG(细胞流式同型对照)
xy-0294xy-xyE Goat IgG/PE荧光素PE标记羊IgG(细胞流式同型对照)
xy-0293xy-xyE Rat IgG/PE荧光素PE标记大鼠IgG(细胞流式同型对照)
xy-0326xy-xyE Bovine IgG/PE荧光素PE标记牛IgG
xy-0327xy-xyE Bovine IgM/PE荧光素PE标记牛IgM
xy-0310xy-xyE Chicken IgG/PE荧光素PE标记鸡IgG
xy-0314xy-xyE Chicken IgM/PE荧光素PE标记鸡IgM
xy-0373xy-xyE dog IgM/PE荧光素PE标记狗IgM
xy-0370xy-xyE Goat IgM/PE荧光素PE标记羊IgM
xy-0358xy-xyE Guinea IgG/PE荧光素PE标记豚鼠IgG
xy-0375xy-xyE Guinea IgM/PE荧光素PE标记豚鼠IgM
xy-0308xy-xyE Horse IgG/PE荧光素PE标记马IgG
xy-0374xy-xyE Horse IgM/PE荧光素PE标记马IgM
xy-0297xy-xyE human IgG/PE荧光素PE标记人IgG
xy-0345xy-xyE human IgM/PE荧光素PE标记人IgM
xy-0360xy-xyE human IgA/PE荧光素PE标记人IgA
xy-0335xy-xyE Monkey IgG/PE荧光素PE标记猴IgG
xy-0336xy-xyE Monkey IgM/PE荧光素PE标记猴IgM
xy-0368xy-xyE Mouse IgM/PE荧光素PE标记小鼠IgM
xy-0309xy-xyE pig IgG/PE荧光素PE标记猪IgG
xy-0777xy-xyE Mink IgG/PE荧光素PE标记水貂IgG
xy-0369xy-xyE Rabbit IgM/PE荧光素PE标记兔IgM
xy-0346xy-xyE Rat IgM/PE荧光素PE标记大鼠IgM
xy-0884xy-xyE rHIL-1Ra/PE荧光素PE标记重组人白介素-1受体拮抗剂
xy-0789xy-xyE Insulin/PE荧光素PE标记猪胰岛素蛋白
xy-xy0002-xyE KLH/PE荧光素PE标记血蓝蛋白
xy-0945xy-xyE Albumin /PE荧光素PE标记人血白蛋白
xy-2179xy-xyE AACT/PE荧光素PE标记胰糜蛋白酶