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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
单克隆
- 抗体英文名:
Anti-ARα1/ADRA1B(α1-
- 抗体名:
alpha 1肾上腺素能受体抗体
alpha 1-adrenergic receptor有兴奋效应也有抑制效应。肾上腺素能受体又可分为α和β两种。alpha 受体与儿茶酚胺结合后,主要是兴奋平滑肌,如血管收缩、子宫收缩和瞳孔开张肌收缩等;但也有抑制作用,如使小肠平滑肌舒张。β受体又可分为β1和β2两个亚型
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region.
mol wt:57kDa
Other Aliases:
ADRA1; ADRA1A; ADRA1B; ADRA1C; ADRA1D; ADRA1L1; ADRA1R; Adrenergic alpha 1A receptor; Adrenergic alpha 1B receptor; Adrenergic alpha 1C receptor; Adrenergic alpha 1D receptor; Alpha 1A adrenergic receptor; Alpha 1A adrenoceptor; Alpha 1A adrenoreceptor; Alpha 1C adrenergic receptor; Alpha 1D adrenergic receptor; Alpha 1D adrenoceptor; Alpha 1D adrenoreceptor; Alpha adrenergic receptor 1a; Alpha adrenergic receptor 1b; Alpha adrenergic receptor 1c; Alpha adrenergic receptor 1d; Alpha1; ALPHA1AAR; DAR; dJ779E11.2
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alpha 1肾上腺素能受体抗体
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文献和实验[1]肾上腺髓质的激素(广义的),1901年高峰让吉氏从肾上腺髓质提纯并加以结晶化,命名为adrenalin(当时特认名)。同年,J.J.Abel和T.B.Aldrich也分别将其结晶化,F.Stolz(1904)合成成功。亦称epirenamin(日本药典),epineph-rine(美、英药典)或adrenalin。融点212℃(分解)。天然的肾上腺素为L型,其生理作用比D型的强15倍。肾上腺素可由苯丙氨酸合成。能使内脏、皮肤、粘膜、肾脏、脑的小动脉平滑肌收缩,但小剂量可使骨骼
【求助】矛盾的实验结果:IKb alpha和NFKB同时升高
吴佰霖 我的基因过表达,结合文献,推理应该是IKb alpha下降,而NFKB升高 (IKb可磷酸化NFKB,使后者降低) 但现在我的结果是两者同时升高,请问可能的原因有哪些呢? 谢谢 woxingwosu 可否检测一下NFKB的磷酸化情况? erik NFKB是检测核内的吗?检测p65还是p50/ 吴佰霖 检测总蛋白
原文也可写做 norepinephrine或 L- arterenol。它是从副肾髓质和肾上腺素一起被提取出来的激素(广义)。在哺乳动物中,它从交感神经的末端作为化学传递物质被分泌出来。是从肾上腺素中去掉 N-甲基的物质。牛的副肾髓质里去甲肾上腺素和肾上腺素的含量是 1∶ 4( 1份去甲肾上腺素, 4份肾上腺素)。市售的肾上腺素含有 10— 20%的去甲肾上腺素。其作用如表所示与肾上腺素类似,但在量上和或质上均稍有差别。去甲
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