Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection. This antibody recognizes human TNF-alpha in ELISA.
克隆类型:
Mouse Monoclonal Antibody
亚型:
Mouse IgG2a
免疫原:
Recombinant human TNF-alpha protein
适用物种:
H
应用范围:
E
应用说明:
Cat. No. 250108 (HRP-conjugated format) can be used as the detection antibody in a sandwich ELISA format with Cat. No. 254525 as capture antibody. E: 1 ug/ml