- ￥2400
- PLLABS
- 加拿大
- PL0304896
- 2025年07月10日
- WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
- Mouse
- Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Rab
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- 详细信息
- 技术资料
- 免疫原：
Peptide derived from human Presenilin-1 CTF subunit.
- 亚型：
Mouse Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
单克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Rab
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0304896
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Mouse
- 应用范围：
WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
- 浓度：
1mg/ml
- 靶点：
presenilin 1/PS-1 (CT)
- 抗体英文名：
presenilin 1/PS-1 (CT) Antibody
- 抗体名：
早老素蛋白-1抗体
- 规格：
0.1ml
presenilin 1/PS-1 (CT) Antibody
Cat#：PL0304896
Isotype:Mouse Polyclonal IgG
Immunogen：Peptide derived from human Presenilin-1 CTF subunit.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1;PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes.
Alternate Names：
Presenilin-1 CTF subunit; AD 3; AD3; Ad3h; Alzheimer Disease 3; EC 3.4.23.; FAD; Homo Sapiens Clone CC44 Senilin 1; Presenilin 1 Alzheimer disease 3; Presenilin 1; Presenilin-1 CTF12; PS1-CTF12; Presenilin1; Protein S182; PS 1; PS-1; PS1; PSEN 1; PSEN1; PSN 1; PSN1; PSN1_HUMAN; PSNL 1; PSNL1; S182; S182 Protein; Senilin 1; Senilin1.
Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Rab
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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presenilin 1/PS-1 (CT) Antibody
￥2400
