- ￥3000 - 3999
- Abbiotec
- 美国
- 250619
- 2025年07月16日
- E, WB, IHC
- Rabbit
- H, M, R, B, D, Ck
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cyclin C.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H, M, R, B, D, Ck
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
Cyclin C
- 抗体英文名：
Cyclin C Antibody
- 抗体名：
Cyclin C Antibody
- 规格：
0.1 mg
Cyclin C Antibody产品详细介绍：
| 产品名称： | Cyclin C Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/cyclin-c-antibody【参考图片】 |
| 货号： | 250619 |
| 规格： | 0.1 mg |
| 产品描述： | Cyclin-C (CCNC) forms the CDK8 module with CDK8, MED12, MED13, which decreases transcriptional activation when combined with the Mediator complex. The Mediator complex is a large protein complex composed of almost 30 different MED proteins that regulates transcription of nearly all RNA polymerase II (RNApII)-dependent genes, conveying information from gene-specific regulatory proteins. Mediator serves as a scaffold for the assembly of the functional preinitiation complex that includes RNApII. Cyclin-C-bound CDK8 phosphorylates the C-terminal domain of the large subunit of RNApII, inhibiting the formation of a transcription initiation complex. Cyclin-C is phosphorylated upon DNA damage, probably by ATM or ATR. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cyclin C. |
| 适用物种： | H, M, R, B, D, Ck |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名： | Cyclin-C; Cyclin C; SRB11; CCNC |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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