- ￥3000 - 3999
- Abbiotec
- 美国
- 250561
- 2025年07月15日
- E, WB, IHC
- Rabbit
- H, M, R, Mk, P, B
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BK channel.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and peptide affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H, M, R, Mk, P, B
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
BK Channel
- 抗体英文名：
BK Channel Antibody
- 抗体名：
BK Channel Antibody
- 规格：
0.1 mg
BK Channel Antibody产品详细介绍：
| 产品名称： | BK Channel Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/bk-channel-antibody【参考图片】 |
| 货号： | 250561 |
| 规格： | 0.1 mg |
| 产品描述： | The BK channel (calcium-activated potassium channel subunit alpha-1 or KCNMA1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). BK channel is also activated by the concentration of cytosolic Mg(2+). BK channel has a key role in controlling excitability in a numerous systems, such as smooth muscle contraction, tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. Defects in KCNMA1 are the cause of generalized epilepsy and paroxysmal dyskinesia (GEPD). |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BK channel. |
| 适用物种： | H, M, R, Mk, P, B |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 别名： | Calcium-activated potassium channel subunit alpha-1; Calcium-activated potassium channel, subfamily M subunit alpha-1; Maxi K channel; MaxiK; BK channel; K(VCA)alpha; BKCA alpha; KCa1.1; Slowpoke homolog; slo homolog; Slo-alpha; Slo1; hSlo; KCNMA1; KCNMA; SLO |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and peptide affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验BK Potassium Channel Mutations Affecting Neuronal Function and Epilepsy
. Recently, the large conductance voltage and calcium-activated potassium channel (BK channel) gene and their accessory subunits have been appended to the list of mutations causing epilepsy in humans and mice. BK channels have the specialized role
subunit of the human brain large-conductance, voltage-activated, calcium-sensitive potassium channel (BK channel) are loaded with Rb+ , washed, and then incubated under experimental conditions. The cell supernatant is removed, and the remaining cell
where the combined macroscopic and single channel approach can be employed to study gating mechanisms of the BK type, large conductance, Ca2+ and voltage activated potassium channel in a mammalian expression system. The techniques presented
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