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PRSS10/TMPRSS2 Antibody

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  • ¥2400
  • PLLABS已认证
  • 加拿大
  • PL0300546
  • 2025年07月14日
  • WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 FC: 1:100-500 IF: 1:100-500
  • Rabbit
  • Hu, Mo, Rat, Pig, Cow, Sheep,
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Peptide derived from Hu PRSS10.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Hu, Mo, Rat, Pig, Cow, Sheep,

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0300546

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 FC: 1:100-500 IF: 1:100-500

    • 浓度

      1mg/ml

    • 靶点

      PRSS10/TMPRSS2

    • 抗体英文名

      PRSS10/TMPRSS2 Antibody

    • 抗体名

      丝氨酸蛋白酶10抗体

    • 规格

      0.1ml

    产品细节图片1
    PRSS10/TMPRSS2 Antibody
    Cat#:PL0300546
    Isotype:Rabbit Polyclonal IgG
    Immunogen:Peptide derived from Hu PRSS10.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors (1,2). The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland (3,4). TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain (3). TMPRSS2 is expressed as a full length form and a cleaved protease domain (5) and its expression is increased by androgenic hormones.
    Alternate Names:
    Epitheliasin; PRSS10; Serine protease 10; TMPRSS2; TMPRSS2 ERG FUSION GENE, INCLUDED; TMPRSS2 ETV1 FUSION GENE, INCLUDED; TMPS2_Hu; Transmembrane protease serine 2 catalytic chain; Transmembrane protease, serine 2; Transmembrane protease, serine 2, EC 3.4.219; Transmembrane protease, serine 2, EC 3.4.219; D16Ertd61e.
    Specificity Reaction:Hu, Mo, Rat, Pig, Cow, Sheep,
    Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 FC: 1:100-500 IF: 1:100-500
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

    • Antibody Storage

      inhibitors, and aliquot it for use. Then freeze the aliquots and keep just one around for day to day use at four degrees C. Raw serum containing antibodies: Aliquot into reasonable aliquots (usually 10-50 ml) appropriate to your use of the antibody

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