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- 保存条件:
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- 英文名:
Recombinant Human Melanoma Inhibitory Activity Protein
- 库存:
100
- 供应商:
艾美捷科技
- 规格:
1mg///20ug///5ug
【MIA】重组人黑色素瘤活性抑制蛋白,Recombinant Human Melanoma Inhibitory Activity Protein,MIA
产品名称:【MIA】重组人黑色素瘤活性抑制蛋白-Recombinant Human Melanoma Inhibitory Activity Protein 产品货号:CYT-310 产品规格:1mg///20ug///5ug 来源宿主:大肠杆菌中重组表达
保存建议:【MIA】重组人黑色素瘤活性抑制蛋白-Recombinant Human Melanoma Inhibitory Activity Protein人黑色素瘤活性抑制蛋白(MIA)在室温可保存3周,或置于-18℃冻存用于长期保存.重新溶解后可以在4℃冷藏保存至少2-7天;如果想延长保存时间,建议分装后置于-18℃冻存.请避免反复冻融.
背景资料:The Melanoma Inhibitory protein (MIA) was identified as an inhibitor of in vitro growth of malignant melanoma cells. The protein contains a SH3 domain.MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors,including gliomas,in an autocrine fashion. In a study of human melanoma cell lines with different metastatic capacity MIA mRNA expression appeared to be inversely correlated with pigmentation. MIA has been shown to represent a very sensitive and specific serum marker for systemic malignant melanoma that might be useful for staging of primary melanomas,detection of progression from localized to metastatic disease during follow-up,and monitoring therapy of advanced melanomas.
点击:【MIA】重组人黑色素瘤活性抑制蛋白-Recombinant Human Melanoma Inhibitory Activity Protein查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多prospec公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
ProSpec 是一家全球著名细胞因子蛋白生产和研发的公司,具有20多年的生产经验,专注于蛋白(重组及合成)生产研发。我们的核心产品包括:干扰素、白介素、骨蛋白、肿瘤坏死因子、成纤维生长因子、瘦素、干细胞因子、催乳素、表皮生长因子、胰岛素样生长因子、神经生长因子、集落刺激因子、激素、酶、病毒抗原以及各种重组蛋白等。领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。
艾美捷科技有限公司,通过提供完整的产品和服务体系、便利的客户关系和供应链管理,为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观:“学习、创新、合作、卓越"。作为一家具有尖端的技术实力、的经营管理水平和完善的市场销售体系的生物高科技企业,总部位于武汉光谷高新技术开发区,服务面向全国。艾美捷科技是集进口试剂、实验室耗材销售、技术服务与合约开发为一体的专业化高科技公司,为用户提供最前沿的专业资讯、完备的产品、整合的解决方案,及优质的物流服务。为了更好的服务客户,公司组建了一支经验丰富的研发团队-艾美捷生物技术中心,进入研发生产阶段,将更优质的产品推荐给国内生物领域的同仁们!
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文献和实验p16INK4A and Familial Melanoma
. This phase is controlled by several protein complexes including those consisting of cyclin-dependent kinases (CDK4 and CDK6) and cyclin D. These complexes are inhibited by the INK4 family of proteins—p16INK4A , p15INK4B , p18INK4C , and p19INK4D . Genetic
Evaluation of Rho Family Small G-Protein Activity Induced by Integrin Ligation on Human Leukocytes
Integrin engagement by natural ligands or specific antibodies (Abs) initiates a series of intracellular signaling events that are important for regulating different cell functions, including migration, adhesion, proliferation, differentiation
Melanoma Susceptibility Genes and Risk Assessment
and accounts for approximately 20–50 % of familial melanoma cases. Mutated p16INK4a shows impaired capacity to inhibit the cyclin D1-CDK4 complex, allowing for unchecked cell cycle progression. Mutations in the second protein coded by CDKN2A , p14ARF
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