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- 详细信息
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
HLA-DRA Antibody (Clone # 302CT2.3.2) (HLA-DRA; HLA-DRA1; HLA class II histocompatibility antigen, DR alpha chain; MHC class II antigen DRA)
- 规格:
50 ul
产品名称:HLA-DRA抗体(克隆号302CT2.3.2)|HLA-DRA Antibody (Clone # 302CT2.3.2) (HLA-DRA; HLA-DRA1; HLA class II histocompatibility antigen, DR alpha chain; MHC class II antigen DRA)
【产品形式】:艾美捷为您提供的HLA-DRA抗体(克隆号302CT2.3.2)产品为无色溶液形式,含有50 ul抗体.该产品浓度为与批次相关,溶解于包含有0.09% (W/V)NaN3的粗腹水中.请在收到该HLA-DRA抗体(克隆号302CT2.3.2)产品后,将其置于-20 °C冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Major histocompatibility complex (MHC) class II molecules destined for presentation to CD4+ helper T cells is determined by two key events. These events include the dissociation of class II-associated invariant chain peptides (CLIP) from an antigen binding groove in MHC II å/∫ dimers through the activity of MHC molecules HLA-DM and -DO, and subsequent peptide antigen binding. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM, -DO molecules regulate the dissociation of CLIP and the subsequent binding of exogenous peptides to HLA class II molecules (HLA-DR, -DQ and -DP) by sustaining a conformation that favors peptide exchange. RFLP analysis of HLA-DM genes from rheumatoid arthritis (RA) patients suggests that certain polymorphisms are genetic factors for RA susceptibility. HLA-B belongs to the HLA class I heavy chain paralogs. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. HLA-B and -C can form heterodimers consisting of a membrane anchored heavy chain and a light chain (∫-2-Microglobulin). Polymorphisms yield hundreds of HLA-B and -C alleles.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:HLA-DRA抗体(克隆号302CT2.3.2),查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:HLA-DRA,HLA-DRA抗体(克隆号302CT2.3.2)
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