SIRT7抗体|SIRT7 Antibody （SIR2；

产品名称：SIRT7抗体|SIRT7 Antibody （SIR2； Sirtuin 7； Silent Information Regulator 7）

【产品形式】：艾美捷为您提供的SIRT7抗体产品为无色溶液形式，含有50 ug抗体.该产品浓度为与批次相关，溶解于包含有0.2% gelatin和0.05%NaN3的PBS缓冲液中.请在收到该SIRT7抗体产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.

【背景资料】：The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases （class III HDACs） and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. SIRT7 is a member of this family of proteins and is present in prokaryotes and eukaryotes. All SIR2-like proteins have a sirtuin core domain， which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial， yeast， and mammalian sirtuins are able to metabolize NAD+ and several act as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but as mentioned above， recent reports of histone-activated SIR2-mediated NAD+ metabolism and NAD+-activated SIR2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of SIR2 with NAD+ and the N-ε-acetyl-lysine groups of acetylated histone.

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理， 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.

点击：SIRT7抗体，查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。

关键词：SIRT7，SIRT7抗体