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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
TLR2 Antibody,TLR2,Anti-TLR2,CD282,TIL4,Toll-like receptor 2
- 规格:
100 ug
产品名称:TLR2抗体|TLR2 Antibody,TLR2,Anti-TLR2,CD282,TIL4,Toll-like receptor 2
【产品形式】:艾美捷为您提供的TLR2抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该TLR2抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types is regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulate TLR2, whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:TLR2抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:TLR,TLR2抗体
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文献和实验of the interleukin 1 (IL-1) receptor (IL-1R). TLR2 recognizes the pathogen-associated molecular patterns that are produced by Gram-positive (Gram+) bacterial cell wall components. TLR4, in association with CD14 and a molecule known as MD-2, is crucial
【信息】The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
Review Nature Reviews Immunology 7, 353-364 (May 2007) | doi:10.1038/nri2079 The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling Luke A. J. O'Neill1 & Andrew G. Bowie1 About the authors Summary TLR (Toll-like
Toll-Like Receptors and Rheumatoid Arthritis
in the pathogenesis of RA. Activation of cells by microbial components and also by endogenous molecules via Toll-like receptor (TLR) results in the production of a variety of proinflammatory cytokines, chemokines, and destructive enzymes
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