PTP1B抗体|PTP1B Antibody，Tyrosin

产品名称：PTP1B抗体|PTP1B Antibody，Tyrosine-protein phosphatase non-receptor type 1，Protein-tyrosine phosphatase 1B，PTP-1B，PTP1B

【产品形式】：艾美捷为您提供的PTP1B抗体产品为100 ug 无色溶液，其浓度为0.25 mg/ml，溶解于包含有0.09% （W/V） 叠氮钠的PBS with 0.09% （W/V） sodium azide..请将该PTP1B抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.

【背景资料】：PTP1B is the founding member of the protein tyrosine phosphatase （PTP） family， which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif， which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth， differentiation， mitotic cycle， and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase， as well as JAK2 and TYK2 kinases， which implicated the role of this PTP in cell growth control， and cell response to interferon stimulation.

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点击：PTP1B抗体，查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。

关键词：PTP1B，PTP1B抗体