Calreticulin抗体|Calreticulin An

产品名称：Calreticulin抗体|Calreticulin Antibody，CRP55，CRTC，CALR，Calregulin，cC1qR，ERp60，HACBP，RO，SSA，

【产品形式】：艾美捷为您提供的Calreticulin抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5 mg/ml BSA和0.01%硫柳汞的PBS缓冲液中.请将该Calreticulin抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.

【背景资料】：Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins， it has the conserved ER retention KDEL （Lys-Asp-Glu-Leu） sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites.

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关键词：Calrecticulin，Calreticulin抗体