- 询价
- 艾美捷BioVision
- 美国
- 3075-100
- 2025年07月08日
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- 详细信息
- 文献和实验
- 技术资料
- 克隆性：
多克隆
- 抗体英文名：
Calcineurin A Antibody，PPP3CA，CCN1，CNA1，CALN，CALNA，CALNA1，PPP2B
- 规格：
100 ug
产品名称：Calcineurin A抗体|Calcineurin A Antibody，PPP3CA，CCN1，CNA1，CALN，CALNA，CALNA1，PPP2B
【产品形式】：艾美捷为您提供的Calcineurin A抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Calcineurin A抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
【背景资料】：Calcineurin is a calcium/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit of 61 kDa and a myristylated regulatory B subunit of 19 kDa that binds calcium. The catalytic A subunit consists of an amino terminal catalytic domain， followed by calmodulin and B subunit binding sites， and a caboxyl-terminal autoinhibitory domain. Calnineurin is the target of immunosuppressant drugs such as cyclosporin A and FK506. Calcineurin controls the translocation of nuclear factors of activated T cells （NFAT）， a family of transcriptional activators that control the expression of cytokine genes essential to immune response， from the cytosol into the nucleus of activated T cells. Calcineurin has been proposed to play an important role in mediating calcium-activated cell death.
BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理， 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击：Calcineurin A抗体，查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词：Calcineurin，Calcineurin A抗体
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文献和实验酶(calcineurin)属丝／苏氨酸磷酸酶，其底物是转录因子NF-AT分子已发生磷酸化的丝氨酸和苏氨酸残基。在钙调磷酸酶的作用下，NF-ATp因脱去磷酸根(p)而激活，成为活化的转录因子NF-AT。
Current Status of Lung Transplantation
complications such as renal dysfunction with calcineurin inhibitors. Fibroproliferation inhibitors are used more widely to ameliorate the abnormal healing response to allodependent or alloindependent injury, the latter perhaps related to underrecognized
The Application of ChIP-chip Analysis in the Rice Blast Pathogen
. A more recent variation of this technique is ChIP-seq where DNA sequencing replaces the microarray chip. Here, we describe how we elucidated the binding sites for the Magnaporthe oryzae Ca2+ /calcineurin-dependent transcription factor MoCRZ1 with the ChIP-chip
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