SUMO2/3 多克隆抗体 | SUMO2/3 polycl

【产品形式】：艾美捷为您提供的SUMO2/3 多克隆抗体经过WB, IP, IF等实验验证。推荐使用稀释比率分别为：WB 1:1000-5000, IF 1:100。

【背景资料】：Antibody detects SUMO2 and SUMO3, but not SUMO1 The post-translational modification of cellular proteins by Small Ubiquitin-like Modifier (SUMO) plays a role in a diverse range of biological processes including nuclear protein targeting, formation of sub-nuclear complexes, regulation of transcriptional activities, control of protein stability, chromosome segregation, recovery from checkpoint arrest, DNA damage response and meiosis. SUMOylation of substrate proteins takes place in a manner analogous to that of the ubiquitin conjugation system, utilising E1, E2 and E3 enzymes in an ATP dependent process and often requires a short sequence containing the consensus Ψ-K-X-D/E (where lysine is the modified amino acid, Ψ is a large hydrophobic residue and X is any amino acid residue) on the substrate protein for protein SUMO modification to occur. The SUMO protein family consists of three well accepted members in vertebrates: SUMO1 and the close homologues SUMO2 and SUMO3 with some 50% homology between SUMO1 and SUMO2/3. A fourth family member, SUMO4, has been described though it existence and functional role are still the matter of some debate. Despite their fairly low amino acid sequence identity the SUMO proteins exhibit similar tertiary structures to ubiquitin.

英国Viva Bioscience公司是一家研发、生产并销售蛋白降解相关产品的公司。其产品主要用于细胞自噬、泛素化和蛋白酶体研究（也覆盖其他蛋白降解相关的产品），其产品价格合理、质量可靠且具有创新性。目前VIVA Bioscience提供逾460种产品，涉及细胞自噬、蛋白泛素化和讲解相关的所有试剂盒、蛋白、底物以及多种抑制剂、激活剂等全系列产品。作为多家进口品牌的中国区域总代理，艾美捷科技与Viva Bioscience一道为中国科研工作者们提供更好、更新的自噬、泛素化和蛋白酶体等研究工具。

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