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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
HA 14-1
- 供应商:
艾美捷科技有限公司
- 规格:
25mg
【产品形式】:Autophagy activator. Bcl-2 inhibitor. Apoptosis inducer.
【背景资料】:Cell permeable inhibitor of Bcl-2 (IC50 ~9 μM); acts by binding to the surface pocket. Disrupts Bax / Bcl-2 interaction and induces apoptosis of tumour cells. Also binds to the anti-apoptotic Blc-2 proteins Bcl-XL and Bcl-w. Activates autophagy through disruption of Bcl-2 binding of beclin-1.
英国Viva Bioscience公司是一家研发、生产并销售蛋白降解相关产品的公司。其产品主要用于细胞自噬、泛素化和蛋白酶体研究(也覆盖其他蛋白降解相关的产品),其产品价格合理、质量可靠且具有创新性。目前VIVA Bioscience提供逾460种产品,涉及细胞自噬、蛋白泛素化和讲解相关的所有试剂盒、蛋白、底物以及多种抑制剂、激活剂等全系列产品。作为多家进口品牌的中国区域总代理,艾美捷科技与Viva Bioscience一道为中国科研工作者们提供更好、更新的自噬、泛素化和蛋白酶体等研究工具。
点击HA 14-1查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询Viva Bioscience中国区域授权总代理艾美捷科技有限公司。
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文献和实验protein belongs to the family of 14-3-3 brain protein homologs.Korthout HA; de Boer AHDepartment of Plant Physiology and Biochemistry, Vrije Universiteit, Amsterdam, The NetherlandsPlant Cell 6: 1681-92 (1994)
Introduction of human 14-3-3 proteins
The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14
(2 µg), and 1 µg of purified Ub‐AMC and HA‐tagged Ub‐AMC (HA‐Ub‐AMC). Free Ub (1 µg) was loaded for comparison. (C ) SDS‐PAGE analysis and CBB staining of purified USP14 WT and CA. A known amount of BSA was loaded for comparison. RP2 CP indicates doubly
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