纤溶酶原激活物抑制因子2抗体

纤溶酶原激活物抑制因子2抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

纤溶酶原激活物抑制因子2抗体产品介绍

SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in the placenta, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency. SerpinB2 also inhibits tissue plasminogen activator (t-PA), but with micromolar efficiency, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator. The structure of PAI-2 is not terribly similar to PAI-1, however, which is an E clade serpin.
SerpinB2 is made by many cell types, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein. SerpinB2 is found in saliva, secreted by gingival fibroblasts, and in the skin. SerpinB2 levels are elevated in serum during pregnancy, and in leukemia, breast cancer and ovarian cancer, although it was lowered in some cancers.A shorter SerpinB2 isoform of 382 amino acids, has been reported, with a predicted mass of 43.1 kDa and a pI of 5.69. The shorter form has a deletion just after the start of the mature protein, but it is unclear what the relative production and distribution is for the shorter sequence. xy-1823R IGFBP4/IBP4胰岛素样生长因子结合蛋白4抗体
xy-1816R ITGA7整合素α7抗体
xy-1811R IL-7白介素7抗体
xy-1805R IL-6R alpha白细胞介素6受体α/IL-6Rα抗体
xy-2428R IL-9白介素9抗体
xy-1804R Integrin alpha L整合素αL抗体Integrin αL
xy-1578R Interferon alpha干扰素α抗体
xy-3402R Phospho-INPPL1(Ser576)磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体
xy-3404R Phospho-INPPL1(Tyr986 + Tyr987)磷酸化肌醇聚磷酸盐磷酸酶样蛋白1抗体
xy-1826R Inhibin Beta C抑制素βC抗体
xy-1830R IL-16白介素16抗体
xy-1825R Inhibin beta B抑制素βB/Inhibin β B抗体
xy-1827R IL-11白介素11抗体
xy-2624R IL-22R白介素22受体抗体
xy-2626R IL-26/AK155白介素26抗体
xy-2612R IL-17D/IL-27白介素-17D抗体
xy-15531R IBRDC1环指蛋白217抗体
xy-0605R IL-2白介素2抗体(人)
xy-1460R IL-23R白介素-23受体抗体
xy-1434R IGFBP3胰岛素样生长因子结合蛋白3抗体
xy-1459R IL-6R Beta/CD130/gp130白细胞介素6受体β抗体IL-6Rβ
xy-1463R IFNGR1干扰素-gamma受体1抗体
xy-10540R IL-1 Alpha Propeptide白介素1α前肽/IL-1α前肽抗体
xy-13771R ITGA11整合素α11抗体
xy-15571R IGFL2胰岛素生长因子样家族成员2抗体
xy-15540R IDI2异戊烯基焦磷酸异构酶2抗体
xy-2784R ITKIL-2诱导型T细胞激酶抗体
纤溶酶原激活物抑制因子2抗体